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RpoB polymorphisms in Mycobacterium tuberculosis complex from a population in G...
Sutre, AF; Sanca, A; Mané, A; Henriques, V; Portugal, C; Sancho, L; Cardoso, A; Paixão, E; Queico, CQF; Salem, JI; Antunes, A; Duarte, EL; David, SThe global tuberculosis (TB) threat is diffi cult to evaluate in countries with scarce laboratory facilities where little is known about the genetic basis of drug resistance, including the rpoB RRDR (rifampicin resistance determining region) of the Mycobacterium tuberculosis complex (MTC). The present study aimed at performing a preliminary evaluation of rpoB polymorphisms in a DNA set of MTC isolates from Guin...
Tuberculosis diagnosis after bleach processing for early stage tuberculosis lab...
David, Susana; Sutre, AF; Sanca, A; Mané, A; Henriques, V; Portugal, Clara; Sancho, Luísa; Cardoso, A; Paixão, Eleonora; Duarte, EL; Leite, CQFThe diagnosis of tuberculosis is seriously hampered in the absence of standard biosafety laboratory facilities for specimen concentration and Mycobacterium tuberculosis culture. Within a laboratory twinning arrangement,heat-fixed direct smear and sediment from 74 bleach-processed and 20 non-processed specimens from Cumura Hospital, Guinea-Bissau, were sent to Lisbon for molecular evaluation of rifampicin resist...
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