The release of the opioid antagonist naltrexone from neutral poly(N-isopropylacrylamide) (PNIPAAM)microgels and negatively charged PNIPAAM microgels containing acrylic acid groups (PNIPAAM-co-PAA) has been studied at various microgel and drug concentrations. The release curves were found to be well represented by the Weibull equation. The release rates were observed to be dependent on the microgel concentration...
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