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Actin cytoskeleton disruption is an early event upon exposure of cerebellar gra...
Tiago, Teresa; Silva, D.; Samhan-Arias, A. K.; Aureliano, M.; Gutiérrez-Merino, CarlosIn this work we have studied the alterations of the actin cytoskeleton in cultured cerebellar granule neurons during exposure to the peroxynitritereleasing agent SIN-1 for less than 2 hours. Actin polymerization state was assessed by fluorescence microscopy ratio images using double labelling for actin filaments (phallacidin) and monomers (DNase-I). In addition, agonists and antagonists of L-type Ca2+ channels ...
Data: 2009
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Origem: Sapientia - Universidade do Algarve
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