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Activity of Thymus capitellatus volatile extract, 1,8-cineoleand borneol agains...
Machado, M.; Dinis, A. M.; Santos-Rosa, M.; Alves, V.; Salgueiro, L.; Cavaleiro, C.; Sousa, M. C.In the search for new leishmanicidal agents, Thymus capitellatus Hoffmanns. & Link (familyLamiaceae) volatile extract and its major compounds, 1,8-cineole and borneol, were testedagainst Leishmania infantum, Leishmania tropica and Leishmania major. Plant volatile extract(essential oil) was analysed by GC and GC–MS and the activity of essential oil on Leishmaniapromastigotes viability was assessed using tetrazol...
Activity of Thymus capitellatus volatile extract, 1,8-cineole and borneol again...
Machado, M.; Dinis, A. M.; Santos-Rosa, M.; Alves, V.; Salgueiro, L.; Cavaleiro, C.; Sousa, M. C.In the search for new leishmanicidal agents, Thymus capitellatus Hoffmanns. & Link (family Lamiaceae) volatile extract and its major compounds, 1,8-cineole and borneol, were tested against Leishmania infantum, Leishmania tropica and Leishmania major. Plant volatile extract (essential oil) was analysed by GC and GC–MS and the activity of essential oil on Leishmania promastigotes viability was assessed using tetr...
Preliminary studies for the aplication of Thymbra capitata essential oil as pot...
Machado, Daniela Marlene da Silva; Alves, P.; Sousa, Cláudia; Oliveira, J. Martinez de; Salgueiro, L.; Oliveira, A. Palmeira de; Cerca, NunoBacterial vaginosis (BV) is the most common gynecological clinical condition in women in reproductive age, and has been associated with an increased risk of development of preterm labor, spontaneous abortion, and several sexually transmitted diseases such as HIV [1]. BV is not only a condition that involves excessive growth of anaerobic microorganisms, but also involves the presence of an adherent biofilm [2]. ...
Screening of five essential oils for identification of potential inhibitors
Neves, A; Rosa, S; Gonçalves, J; Rufino, A; Judas, F; Salgueiro, L; Lopes, MC; Cavaleiro, C; Mendes, AFNuclear factor-kappaB is a key transcription factor activated by pro-inflammatory signals, like interleukin-1beta (IL-1), being required for the expression of many inflammatory and catabolic mediators, such as nitric oxide (NO), that play an important role in arthritic diseases. This work aimed at screening and identifying natural inhibitors of IL-induced NF-kappaB activation and NO production in human articula...
Composition and antifungal activity of the essential oil of Mentha cervina from...
GonÇalves, M. J.; Vicente, A. M.; Cavaleiro, C.; Salgueiro, L.The chemical composition of the essential oils obtained by hydrodistillation from the aerial parts of Mentha cervinacollected during the flowering and vegetative phases of the plants were investigated by GC and GC-MS. Quantitative differences were observed in the compositions, particularly in the amounts of pulegone (12.9–79.6%) and isomenthone (8.7–77.0%). Antifungal activity of the oils was evaluated by minim...
Composition and variability of the essential oils of the leaves and berries fro...
Cavaleiro, C.; Salgueiro, L. R.; Cunha, A. P. da; Figueiredo, A. C.; Barroso, J. G.; Bighelli, A.; Casanova, J.The compositions of the essential oils isolated from leaves and berries of Juniperus navicularis Gand., an endemic species from Portugal, were investigated by GC and GC-MS. Oils from representative samples of populations as well as from individual samples were studied. The oils consisted mainly of monoterpene hydrocarbons (67.1-88.0% and 61.7% for leaf and berry oils, respectively). [alpha]-Pinene (6.3-38.0%), ...
Chemical polymorphism of the essential oils from populations of Thymus caespiti...
Pereira, S. I.; Santos, P. A. G.; Barroso, J. G.; Figueiredo, A. C.; Pedro, L. G.; Salgueiro, L. R.; Deans, S. G.; Scheffer, J. J. C.The compositions of the essential oils isolated from the aerial parts of 11 populations of Thymus caespititius collected during the flowering phase on Pico, Faial and Graciosa (Azores) were studied by GC and GC-MS. The monoterpene fraction was dominant in all the oils analysed (55-90%) and consisted mainly of oxygen-containing compounds (44-79%). Sesquiterpenes represented an important fraction of the oils from...
Chemical polymorphism of the essential oils from populations of Thymus caespiti...
Pereira, S. I.; Santos, P. A. G.; Barroso, J. G.; Figueiredo, A. C.; Pedro, L. G.; Salgueiro, L. R.; Deans, S. G.; Scheffer, J. J. C.The compositions of the essential oils obtained from ten populations of Thymus caespititius grown on S. Jorge (Azores) were studied by GC and GC-MS. All the oils analysed were dominated by their monoterpene fraction (69-91%). The sesquiterpene fraction was rather small (4-17%) and consisted mainly of oxygen-containing compounds (3-13%). Enantiomeric ratio of sabinene and [alpha]-terpineol was investigated in th...
Essential oils from four Piper species
Martins, A. P.; Salgueiro, L.; Vila, R.; Tomi, F.; Cañigueral, S.; Casanova, J.; Cunha, A. Proença da; Adzet, T.The essential oils from Piper capense, P. nigrum, P. guineense and P. umbellatum from S. Tomé e Príncipe were investigated for the first time. They were analysed by GC, GC-mass spectrometry and 13C NMR. Monoterpene hydrocarbons were the main group of constituents in three of the samples (P. capense, P. nigrum and P. umbellatum), whereas for the other species (P. guineense) phenylpropanoid derivatives were the m...
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