Encontrados 112 documentos, a visualizar página 1 de 12
História térmica do grupo do Flysch do Baixo Alentejo, Zona Sul Portuguesa
Rodrigues, Bruno; Chew, Dave; Jorge, R. C. G. S.; Fernandes, PauloCom objectivo de reconstruir a história térmica do Grupo Flysch Baixo Alentejo foi realizado um estudo sistemático com o auxílio de duas metodologias complementares: medição do poder reflector da vitrine e datações de traços de fissão de apatites contidas em grauvaques das formações de Mértola, Mira e Brejeira.
Juvenile systemic sclerosis: review of 15 patients
Sousa, S.; Fernandes, S.; Estanqueiro, P.; Zilhão, C.; Resende, C.; Ramos, F.; Salgado, M.; Guedes, M.; Gomes, J.; Santos, M.
[15]aneN4S: synthesis, thermodynamic studies and potential applications in chel...
Torres, N.; Gonçalves, S.; Fernandes, A. S.; Machado, J. F.; de Brito, M. J.; Oliveira, N. G.; Castro, M.; Costa, J.; Cabral, M. F.The purpose of this work was to synthesize and characterize the thiatetraaza macrocycle 1-thia-4,7,10,13-tetraazacyclopentadecane ([15]aneN4S). Its acid-base behaviour was studied by potentiometry at 25 °C and ionic strength 0.10 M in KNO3. The protonation sequence of this ligand was investigated by 1H-NMR titration that also allowed the determination of protonation constants in D2O. Binding studies of [15]aneN...
Sr and Nd isotope data for arc-related (meta) volcanics (SW Iberia)
Santos, J. F.; Mata, J.; Ribeiro, S.; Fernandes, J.; Silva, J.In the southern sector of the Ossa-Morena Zone (Iberian Variscan Chain), along its boundaries with the Beja-Acebuches Ophiolite and the South-Portuguese Zone, Upper Palaeozoic igneous mafic and intermediate rocks, both intrusive and extrusive, are widely represented. The so-called Odivelas Unit (Andrade,1983), include (meta-) basalts and (meta-) andesites, which, according with previous studies, display low-K ...
Idades U-Pb de zircões detríticos do Grupo do Flysch do Baixo Alentejo, Zona Su...
Rodrigues, Bruno; Chew, Dave; Jorge, R. C. G. S.; Fernandes, Paulo; Veiga-Pires, C.; Oliveira, José TomásForam obtidas idades U-Pub através de ablasão a lazer de zircões detríticos das formações do Grupo Flysch Baixo Alentejo.
Mechanistic insights into the cytotoxicity and genotoxicity induced by glycidam...
Bandarra, S; Fernandes, AS; Magro, I; Guerreiro, PS; Pingarilho, M; Churchwell, MI; Gil, OM; Batinic-Haberle, I; Gonçalves, S; Rueff, J; Miranda, JPAcrylamide (AA) is a well-known industrial chemical classified as a probable human carcinogen. Benign and malignant tumours at different sites, including the mammary gland, have been reported in rodents exposed to AA. This xenobiotic is also formed in many carbohydrate-rich foods prepared at high temperatures. For this reason, AA is an issue of concern in terms of human cancer risk. The epoxide glycidamide (GA)...
Differential effects of methoxyamine on doxorubicin cytotoxicity and genotoxici...
Guerreiro, P. S.; Fernandes, A. S.; Costa, J. G.; Castro, M.; Miranda, J. P.; Oliveira, N. G.Pharmacological inhibition of DNA repair is a promising approach to increase the effectiveness of anticancer drugs. The chemotherapeutic drug doxorubicin (Dox) may act, in part, by causing oxidative DNA damage. The base excision repair (BER) pathway effects the repair of many DNA lesions induced by reactive oxygen species (ROS). Methoxyamine (MX) is an indirect inhibitor of apurinic/apyrimidinic endonuclease 1 ...
Ocorrências hidrominerais do Nordeste transmontano: origens das mineralizações ...
Lima, Alberto S.; Fernandes, Luís Filipe; Santos, Rui P.O presente estudo centra-se na caraterização física e isotópica de quatro ocorrências hidrominerais sulfúreas da região de Trás-os-Montes Oriental(NE de Portugal, visando a elaboração de modelos conceptuais do funcionamento hidrogeológico, numa perspetiva de avaliação do potencial hidromineral do nordeste transmontano.
Preliminary evaluation of bacteriocinogenic potencial of Lactobaccilli isolates...
Gonçalves, S.; Fernandes, H.; Fernandes, M. J.; Barreto, A.; Elias, M.; Fraqueza, M.J.The fermented and dry meat sausages presents relevant importance in the south of Europe gastronomy, namely in Portugal. According to the increased consumer concern regarding health and food safety, and simultaneously the abusive use of chemical products to control pathogenic flora, it is essential to get knowledge about bacteriocinogenic and technological properties provided by starter strains in meat products....
Cytotoxic effects of cadmium in mammary epithelial cells: Protective role of th...
Gonçalves, S; Fernandes, A. S.; Oliveira, N. G.; Marques, J.; Costa, J.; Cabral, M. F.; Miranda, J.; Cipriano, M.; Guerreiro, P. S.; Castro, M.Human exposure to cadmium (Cd) occurs via different routes, including diet. The increasing amount of data linking Cd with different cellular effects in the mammary gland justifies additional toxicological assessments using human mammary epithelial cells. This work aimed therefore to assess the cytotoxic effects of Cd in MCF10A cells and to characterize the cytoprotective role of the macrocycle [15]pyN5 in the f...
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