The study took place at the Vez River that belongs to the Lima River basin and Minho and Lima region basin located in the municipality of Arcos de Valdevez. Due to its diversity of habitat and species that shelter the Vez River area were classified as Site of Community Importance (SCI) for the Conservation. The aim of this work were conducting inventory and characterization of the fish population, the ecologica...
The authors acknowledge Margarida Correia-Neves and Catarina L. Santos for helpful comments and suggestions ; Tuberculosis (TB) is a global health problem estimated to kill 1.4 million people per year. Recent advances in the genomics of the causative agents of TB, bacteria known as the Mycobacterium tuberculosis complex (MTBC), have allowed a better comprehension of its population structure and provided the fo...
Heterotrimeric G-protein-mediated signaling pathways play a pivotal role in transmembrane signaling in eukaryotes. Our main aim was to identify signaling pathways regulated by A. nidulans GprB and GprD G-protein coupled receptors (GPCRs). When these two null mutant strains were compared to the wild-type strain, the DeltagprB mutant showed an increased protein kinase A (PKA) activity while growing in glucose 1% ...
o characterize the mechanisms involved in glucose transport, in the filamentous fungus Aspergillus nidulans, we have identified four glucose transporter encoding genes hxtB-E. We evaluated the ability of hxtB-E to functionally complement the Saccharomyces cerevisiae EBY.VW4000 strain that is unable to grow on glucose, fructose, mannose or galactose as single carbon source. In S. cerevisiae HxtB-E were targeted ...
In this work three different hydrogels were developed to associate, as vehicles, with the synthetic bone substitute GR-HA. One based on an alginate matrix (Alg); a second on a mixture of alginate and chitosan (Alg/Ch); and a third on alginate and hyaluronate (Alg/HA), using Ca2+ ions as cross-linking agents. The hydrogels, as well as the respective injectable bone substitutes (IBSs), were fully characterized fr...
There are a few applications in which stairs must be detected, for example for aiding blind persons during navigation and for autonomous robots which must rely on vision. . In this paper we present a very simple algorithm for detecting stairs, both in indoor and outdoor environments, when the camera is at a distance of approximately five meters from the stairs. The problem is hard to solve due to different factor...
This work will present a complete methodology concerning experimental, modelling and simulation results. Both the CHIRALPAK AD and CHIRALPAK IA CSP will be evaluated. The selection of the proper CSP/solvent combination for preparative operation will be fully study taking into account the screening strategy proposed by Zhang et al. Additional results include the measurement of nadolol stereoisomers solubilities,...
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