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Optimization of mobile phase composition in simulated moving bed chiral separat...
Ribeiro, António E.; Sá Gomes, P.; Graça, Nuno S.; Pais, L.S.; Rodrigues, A.E.This work will present two case studies; the chiral separation of ketoprofen and flurbiprofen enantiomers, both important examples of non-steroidal anti-inflammatory drugs (NSAIDs), frequently used in the treatment of arthritis and related diseases. A complete methodology concerning experimental, modeling and simulation results will be presented, including the enantiomers solubility and adsorption isotherm meas...
Data: 2010
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Origem: Biblioteca Digital do IPB
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