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Sepsis Mortality Prediction Based on Predisposition, Infection and Response
Moreno, R; Metnitz, B; Adler, L; Hoechtl, A; Bauer, P; Metnitz, P; SAPS 3 InvestigatorsOBJECTIVE: To empirically test, based on a large multicenter, multinational database, whether a modified PIRO (predisposition, insult, response, and organ dysfunction) concept could be applied to predict mortality in patients with infection and sepsis. DESIGN: Substudy of a multicenter multinational cohort study (SAPS 3). PATIENTS: A total of 2,628 patients with signs of infection or sepsis who stayed in the ...
Modeling in-Hospital Patient Survival During the First 28 Days After Intensive ...
Moreno, R; Metnitz, P; Metnitz, B; Bauer, P; Afonso de Carvalho, S; Hoechtl, A; SAPS 3 InvestigatorsOBJECTIVE: The objective of the study was to develop a model for estimating patient 28-day in-hospital mortality using 2 different statistical approaches. DESIGN: The study was designed to develop an outcome prediction model for 28-day in-hospital mortality using (a) logistic regression with random effects and (b) a multilevel Cox proportional hazards model. SETTING: The study involved 305 intensive care unit...
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