Encontrados 45 documentos, a visualizar página 1 de 5
Síndrome de Wolfram. A Propósito de Um Caso Clínico
Figueiredo, Ana Cristina; Pinto, Eduarda; Frutuoso, Simão; Dores, Jorge; Carvalho, Rui; Alves, ValterA síndrome de Wolfram, inicialmente descrita em 1938, caracteriza-se pela associação de Diabetes Mellitus, atrofia óptica e de forma mais inconstante surdez, Diabetes Insípida, alterações urinárias e neurológicas. Esta síndrome, frequentemente familiar, tem uma transmissão autossómica recessiva, tendo sido descrita recentemente uma ligação a marcadores no braço curto do cromossoma 4.Descreve-se o caso de uma me...
Feeding strategy assessment through fatty acid profiles in muscles of adult sea...
Lança, Maria João; Machado, Maria; Ferreira, Rui; Alves-Pereira, Isabel; Quintella, Bernardo; Almeida, Pedro R.The fatty acid signature of sea lamprey Petromyzon marinus (L.) muscle was used as a tool to detect feeding strategies used during the parasitic marine trophic phase of the species. Adult sea lampreys were collected near the mouth of six Portuguese rivers (Minho, Lima, Douro, Vouga, Mondego and Tagus) and muscle fatty acid profile was characterized. The analysis of fatty acid composition of muscle neutral lipid...
How does heat-shock affect the influence of titanium dioxide nanoparticles in g...
Capela-Pires, J; Ferreira, Rui; Alves-Pereira, IsabelNanomaterials include all substances that contain nanoscale structures sized between 1 and 100 nm. At this size, the characteristics of materials change: their strength, conductivity, and reactivity, which differ substantially from macro- or micron- sized materials, shifting the rules of physics and chemistry to the sidelines. Although, the geological origin and the ubiquitous occurrence of nanoparticles in the...
Enzyme activity profile of peroxidases and polifenoloxidases of Malus domestica...
Agostinho, J; Ferreira, Rui; Alves-Pereira, IsabelThe region of Beira Alta, Portugal distinguishes itself as a favorable area for apple growing that produces fruits with great economic importance. The polyphenoloxidase (EC 1.14.18.1, PPO) a copper-enzyme located in plastids, catalyzes the oxidation of phenols to quinones present in the vacuoles, generating brown coloration products. In general, the enzymatic browning occurs when phenolic compounds are released...
Titanium dioxide nanoparticles inhibits Saccharomyces cerevisiae BY4741 prolife...
Capela-Pires, J; Ferreira, Rui; Alves-Pereira, Isabelphysicochemical properties are poorly known. In the case of metal nanoparticles, their dimension is often important, since their surface area increases as molecular size decreases, causing alterations in their magnetic and thermodynamic properties. Consequently, the influence they exert on life is an attractive topic of research in biochemical toxicology by the novelty of their behavior. Although titanium diox...
Ability to scavenge free radicals by Malus domestica Borkh pulp reversed the st...
Agostinho, J; Ferreira, Rui; Alves-Pereira, IsabelThe determination of functional value of a particular food includes the discovery and characterization of their antioxidant properties, as its phenols contents, its ability to scavenge reactive oxygen species (ROS) or its biological activity to reverse oxidative stress markers, as triggered by vanadium (V) in eukaryotic models as S. cerevisiae, which exhibit high homology between their enzyme antioxidant respon...
Nanoparticles of titanium dioxide modulate the response to temperature by key e...
Capela-Pires, J; Ferreira, Rui; Alves-Pereira, IsabelNanotechnology can be used to obtain materials at nanoscale (<100 nm) with new physicochemical and structural properties which depend on particle size and, probably, may trigger new biological effects. As Saccharomyces cerevisiae is an excellent model for study molecular and cell biology responses is growingly used in the toxicological evaluation of chemicals, such as heavy metals or nanoparticles of metal oxid...
Nanopartículas de dióxido de titânio revertem a repressao catabólica pela glico...
Capela-Pires, J; Ferreira, Rui; Alves-Pereira, IsabelA nanotecnologia liberta para o ambiente materiais com dimensão entre 1 e 100 nm, cujas propriedades magnéticas e termodinâmicas, maioritariamente condicionadas pela área superficial/dimensão molecular, determinam o tipo de interacção que estabelecem com as biomoléculas. A caracterização dos efeitos biológicos das nanopartículas constitui assim um tema de investigação aliciante em toxicologia bioquímica, pelo s...
Implementation of an information technology infrastructure library process – th...
Esteves, Rui; Alves, PauloThis paper presents the preliminary results of an academic research about implementation of an Information Technology Infrastructure Library (ITIL) process conducted in 2012 in a Portuguese public organization named Culture, Tourism and Transport Regional Department of Madeira Autonomous Region. During the process we encountered resistance against ITIL and adversity to change. It is also true that other factors...
Implementação do processo gestão da configuração da framework ITIL
Esteves, Rui; Alves, PauloEste artigo apresenta o resultado de uma investigação académica sobre a Gestão de Serviços de Tecnologias de Informação (GSTI) realizada num organismo público na Região Autónoma da Madeira (RAM), a Secretaria Regional da Cultura, Turismo e Transportes (SRT) em 2012. Optou-se pelo processo Gestão da Configuração do Information Technology Infrastructure Library (ITIL), como um modelo a implementar nesta organizaç...
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