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Biomimetic Ca-P coatings Incorporating bisphosphonates produced on starch-based...
Oliveira, A. L.; Pedro, A. J.; Saiz-Arroyo, C.; Mano, J. F.; Rodriguez, G.; Roman, J. San; Reis, R. L.In this study, sodium clodronate, a well-known therapeutic agent from the family of bisphosphonates (BPs), is incorporated in a biomimetic calcium phosphate (CaP) coating, previously formed on the surface of a starch-based biomaterial by a sodium silicate methodology, as a strategy to develop a site-specific drug delivery system for bone tissue regeneration applications. The effects on the resulting CaP coating...
Influence of beta-radiation sterilisation in properties of new chitosan/soybean...
Silva, R. M.; Elvira, C.; Mano, J. F.; Roman, J. San; Reis, R. L.Novel chitosan (cts) and soybean protein isolate (SI) blended membranes were prepared. These membranes were produced by solvent casting. Besides combining the advantages of both materials, cts/SI membranes exhibit a biphasic structure that will eventually originate in situ porous formation, through a two-step degradation mechanism. In this particular work the effect of beta-radiation over the properties of thes...
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