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Eigenvalue computations in the context of data-sparse approximations of integra...

Roman, J. E.; Vasconcelos, P. B.; Nunes, A. L.

In this work, we consider the numerical solution of a large eigenvalue problem resulting from a finite rank discretization of an integral operator. We are interested in computing a few eigenpairs, with an iterative method, so a matrix representation that allows for fast matrix-vector products is required. Hierarchical matrices are appropriate for this setting, and also provide cheap LU decompositions required i...

Data: 2013   |   Origem: CiencIPCA

Pharmacological characterization of Solanum cernuum Vell.: 31-norcycloartanones...

Lopes, Luciane C.; Carvalho, João E.; Kakimore, Marise; Vendramini-Costa, Débora B.; Medeiros, Maria Augusta; Spindola, Humberto M.; Ávila-Román, J.

Cycloeucalenone (1) and 24-oxo-31-norcycloartanone (2) obtained from Solanum cernuum Vell. were assayed to explore their pharmacologic roles. Previous studies showed that (2) has selective activity against lung tumor cell line (NCIH460) which expresses high levels of COX-2, suggesting its role in inflammatory process, and also a link between chronic inflammation and cancer-associated process. Dichloromethane cr...

Data: 2013   |   Origem: Repositório do LNEG

Produtividade e valor nutricional da silagem de híbridos de milho em diferentes...

Oliveira,F.C.L.; Jobim,C.C.; Silva,M.S.; Calixto Junior,M.; Bumbieris Junior,V.H.; Roman,J.

Cinco híbridos de milho foram avaliados quanto à produtividade de matéria seca, ao valor nutritivo da silagem e à produtividade de leite. Os híbridos avaliados foram AS 32, AG 9090, CD 308, DKB 747 e P 30F87, colhidos em três alturas de corte: 15, 35 e 55 cm. O delineamento experimental foi em blocos casualizados com parcelas subdivididas e três repetições. Para confecção das silagens, utilizaram-se silos exper...

Data: 2011   |   Origem: OASIS br

Composição física da carcaça e características da carne de bovinos de corte ter...

Roman,J; Jobim,C.C; Resende,F.D; Siqueira,G.R; Faria,M.H; Rivas,R

Avaliou-se o efeito de diferentes dietas sobre as características da carcaça e da carne de bovinos de corte em confinamento: dieta composta por silagem de milho e formulação fixa durante o período de confinamento (SMF); dieta composta por silagem de milho e formulação variável durante o período de confinamento (SMV); dieta composta por silagem de cana-de-açúcar e formulação fixa (SCF); dieta composta por silage...

Data: 2010   |   Origem: OASIS br

Temperature as a single on-off parameter controlling nanoparticles growing, sta...

López Pérez, Paula M.; Silva, Ricardo M. P. da; Pashkuleva, I.; San Román, J. S.; Reis, R. L.


Hydrophobic-electrostatic balance driving the LCST offset aggregation-redissolu...

López Pérez, Paula M.; Silva, Ricardo M. P. da; Pashkuleva, I.; Parra, Francisco; Reis, R. L.; San Román, J.

A series of random terpolymers composed of N-isopropylacrylamide (NIPAAm), 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS), and N-tert-butylacrylamide (NTBAAm) monomers were synthesized by free radical polymerization. The molar fraction of the negatively charged monomer (AMPS) was maintained constant (0.05) for all studied terpolymer compositions. Turbidity measurements were used to evaluate the influence o...


Biomimetic Ca-P coatings Incorporating bisphosphonates produced on starch-based...

Oliveira, A. L.; Pedro, A. J.; Saiz-Arroyo, C.; Mano, J. F.; Rodriguez, G.; Roman, J. San; Reis, R. L.

In this study, sodium clodronate, a well-known therapeutic agent from the family of bisphosphonates (BPs), is incorporated in a biomimetic calcium phosphate (CaP) coating, previously formed on the surface of a starch-based biomaterial by a sodium silicate methodology, as a strategy to develop a site-specific drug delivery system for bone tissue regeneration applications. The effects on the resulting CaP coating...


Innovative approach for producing injectable, biodegradable materials using chi...

Boesel, L. F.; Reis, R. L.; San Román, J.

Although there are a number of injectable biomaterials currently under development, they present some drawbacks such as being based on synthetic polymers, needing toxic or aggressive synthesis procedures or using raw materials with low availability and/or high production costs. Having this in mind, a novel injectable biomaterial using chitooligosaccharides as starting materials was developed. This system uses a...


Transport of small anionic and neutral solutes through chitosan membranes : dep...

Silva, Ricardo M. P. da; Caridade, S. G.; San Román, J.; Mano, J. F.; Reis, R. L.

Chitosan membranes were prepared by solvent casting and cross-linked with glutaraldehyde at several ratios under homogeneous conditions. The cross-linking degree, varying from 0 to 20%, is defined as the ratio between the total aldehyde groups and the amine groups of chitosan. Permeability experiments were conducted using a side-by-side diffusion cell to determine the flux of small molecules of similar size but...


Poly(N-Isopropylacrylamide) surface-grafted ghitosan membranes as a new substra...

Silva, Ricardo M. P. da; López Pérez, Paula M.; Elvira, C.; Mano, J. F.; San Román, J.; Reis, R. L.

The immobilization of poly(N-isopropylacrylamide) (PNIPAAm) on chitosanmembranes was performed in order to render membranes with thermo-responsive surface properties. The aim was to create membranes suitable for cell culture and in which confluent cell sheets can be recovered by simply lowering the temperature. The chitosan membranes were immersed in a solution of the monomer that was polymerized via radical in...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia