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Farnesol induces cell detachment from established S. epidermidis biofilms
Cerca, Nuno; Gomes, F. I.; Bento, Joana C.; França, Ângela; Rolo, Joana; Miragaia, Maria; Teixeira, P.; Oliveira, RosárioAntibiotic resistance is a serious problem in Staphylococcus epidermidis infections as many clinical isolates of this organism are resistant to up to eight different antibiotics. The increased resistance to conventional antibiotic therapy has lead to the search for new antimicrobial therapeutic agents. Farnesol, an essential oil found in many plants, has been shown to be active against S. epidermidis. Using a t...
Farnesol antimicrobial role as biofilm cell detachment inducer in S. epidermidi...
Cerca, Nuno; Gomes, F. I.; França, Ângela; Bento, Joana C.; Rolo, Joana; Miragaia, Maria; Teixeira, P.; Vilanova, Manuel; Oliveira, RosárioObjetives: Farnesol is a naturally-occurring sesquiterpene that was originally isolated from essential oils found in many plants has been described to have antimicrobial potential against several bacteria, including S. epidermidis. However, farnesol mechanism of action is not yet fully understood and some contradictory findings have been reported. We recently described that while farnesol was not efficient at k...
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