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Blood flow in a bifurcation and confluence microchannel : the effectof the cell...

A few detailed studies have been performed in complex in vitro microvascular networks composed by bifurcations and confluences. The main purpose of the present work is to numerically simulate the flow of two distinct fluids through bifurcation and confluence geometries, i. e red blood cells (RBCs) suspended in Dextran40 with about 14% of heamatocrit and pure water. The simulations of pure water and RBCs flows w...

Blood flow in a bifurcation and confluence microchannel : effect of the cell-...

A few detailed studies have been performed in complex in vitro microvascular networks composed by bifurcations and confluences. The main purpose of the present work is to numerically simulate the flow of two distinct fluids through bifurcation and confluence geometries, i. e red blood cells (RBCs)suspended in Dextran40 with about 14% of heamatocrit and pure water. The simulations of pure water and RBCs flows we...

Visualization and measurement of red blood cells flowing in microfluidic devices

Several experimental techniques were performed in the past years using in vitro environments, in an attempt to not only understand the blood flow behaviour in microcirculation but also develop microfluidic devices as an alternative clinical methodology to detect blood diseases. Hence, the visualization and measurement of red blood cells (RBCs) flowing in a microfluidic device are important to provide not only e...

Metodologias de Análise de Legionella em Sistemas de Água

Introdução teórica; Amostragem: (Norma ISO 19458:2006, Water quality- Sampling for microbiological analysis;– Procedimentos internos); Método Cultural; Resultados INSA 2010-2012; Métodos de Biologia Molecular (Real – Time PCR).

Métodos laboratoriais para e identificação de Legonella spp

Legionella species

Prevalência de Legionella nos sistemas de água

Blood flow in microchannels manufactured by a low cost technique: xurography

The xurography is a technique that has been used to make molds to produce microchannels. In contrast to soft lithography [1, 2], xurography uses equipments and materials commonly used in the printing industry, such as cutting plotters, vinyl and other materials. The main advantage of this technique is to fabricate microchannels at a reduced cost [3, 4]. The Fahraeus-Lindqvist effect is a well know phenomenon t...

Flow of red blood cells in microchannel networks : in vitro studies

Human blood is a multiphase biofluid primarily composed by the deformable red blood cells (RBCs) suspended in plasma. Because the complex structure of RBCs, blood exhibits unique flow characteristics on micro-scale level, due to their complex biochemical mechanisms and their response to both shear and extensional flow, which influence the rheological properties and flow behaviour of blood [1,2]. In the past yea...

Separation and deformation of red blood cells in PDMS microchannels

Over the years, several experimental techniques were performed in in vitro environments, in an attempt to understand the flow behaviour of blood in microcirculation. Several of these studies were performed in glass capillaries, and have produced significant results with respect to rheological properties of blood [1, 2]. Another way to perform in vitro blood studies is to use microchannels fabricated by soft- li...