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Automated image analysis of lung branching morphogenesis from microscopic image...

Rodrigues, Pedro L.; Rodrigues, Nuno F.; Duque, Duarte; Granja, Sara; Correia-Pinto, Jorge; Vilaça, João L.

Background: Regulating mechanisms of branching morphogenesis of fetal lung rat explants have been an essential tool for molecular research. This work presents a new methodology to accurately quantify the epithelial, outer contour and peripheral airway buds of lung explants during cellular development from microscopic images. Methods: The outer contour was defined using an adaptive and multi-scale threshold algo...

Data: 2014   |   Origem: CiencIPCA

Automatic modeling of pectus excavatum corrective prosthesis using artificial n...

Rodrigues, Pedro L.; Rodrigues, Nuno F.; Pinho, ACM; Fonseca, Jaime C.; Correia-Pinto, Jorge; Vilaça, João L.

Pectus excavatum is the most common deformity of the thorax. Pre-operative diagnosis usually includes Computed Tomography (CT) to successfully employ a thoracic prosthesis for anterior chest wall remodeling. Aiming at the elimination of radiation exposure, this paper presents a novel methodology for the replacement of CT by a 3D laser scanner (radiation-free) for prosthesis modeling. The complete elimination of...

Data: 2014   |   Origem: CiencIPCA

Variations of the soft tissue thicknesses external to the ribs in pectus excava...

Moreira, António H. J.; Pinto, Jorge Correia; Fonseca, Jaime C.; Vilaça, João L.; Rodrigues, Pedro L.; Pinho, A. C. Marques de; Rodrigues, Nuno F.

BACKGROUND: Surgical repair of pectus excavatum (PE) has become more popular due to improvements in the minimally invasive Nuss procedure. The pre-surgical assessment of PE patients requires Computerized Tomography (CT), as the malformation characteristics vary from patient to patient. OBJECTIVE: This work aims to characterize soft tissue thickness (STT) external to the ribs among PE patients. It also presents ...


Type checking cryptography implementations

Barbosa, Manuel Bernardo; Page, D.; Moss, Andrew; Rodrigues, Nuno F.; Silva, Paulo

Proceedings da conferência Fundamentals of Software Engineering 2011 ; Cryptographic software development is a challenging field: high performance must be achieved, while ensuring correctness and compliance with low-level security policies. CAO is a domain specific language designed to assist development of cryptographic software. An important feature of this language is the design of a novel type system intr...


Pectus Excavatum postsurgical outcome based on preoperative soft body dynamics ...

Moreira, António H. J.; Rodrigues, Pedro L.; Fonseca, Jaime C.; Pinho, A. C. Marques de; Rodrigues, Nuno F.; Pinto, Jorge Correia; Vilaça, João L.

Pectus excavatum is the most common congenital deformity of the anterior chest wall, in which an abnormal formation of the rib cage gives the chest a caved-in or sunken appearance. Today, the surgical correction of this deformity is carried out in children and adults through Nuss technic, which consists in the placement of a prosthetic bar under the sternum and over the ribs. Alth ough this technique has been ...


Thoracic wall reconstruction using ultrasound images to model/bend the thoracic...

Fonseca, João; Moreira, António H. J.; Rodrigues, Pedro L.; Fonseca, Jaime C.; Pinho, A. C. Marques de; Rodrigues, Nuno F.; Pinto, Jorge Correia

Pectus excavatum is the most common congenital deformity of the anterior thoracic wall. The surgical correction of such deformity, using Nuss procedure, consists in the placement of a personalized convex prosthesis into sub-sternal position to correct the deformity. The aim of this work is the CT-scan substitution by ultrasound imaging for the pre-operative diagnosis and pre-modeling of the prosthesis, in order...


Virtual simulation of the postsurgical cosmetic outcome in patients with pectus...

Vilaça, João L.; Moreira, António H. J.; Rodrigues, Pedro L.; Rodrigues, Nuno F.; Fonseca, Jaime C.; Pinho, A. C. Marques de; Pinto, Jorge

Pectus excavatum is the most common congenital deformity of the anterior chest wall, in which several ribs and the sternum grow abnormally. Nowadays, the surgical correction is carried out in children and adults through Nuss technic. This technic has been shown to be safe with major drivers as cosmesis and the prevention of psychological problems and social stress. Nowadays, no application is known to predict t...


The role of coordination analysis in software integration projects

Rodrigues, Nuno F.; Oliveira, Nuno; Barbosa, L. S.

Available for individual study only. ; What sort of component coordination strategies emerge in a software integration process? How can such strategies be discovered and further analysed? How close are they to the coordination component of the envisaged architectural model which was supposed to guide the integration process? This paper introduces a framework in which such questions can be discussed and illustr...


Shacc : a functional prototyper for a component calculus

Martins, André Batista; Barbosa, L. S.; Rodrigues, Nuno F.

For individual study only ; Over the last decade component-based software development arose as a promising paradigm to deal with the ever increasing complexity in software design, evolution and reuse. Shacc is a prototyping tool for component-based systems in which components are modelled coinductively as generalized Mealy machines. The prototype is built as a Haskell library endowed with a graphical user inte...


Slicing for architectural analysis

Rodrigues, Nuno F.; Barbosa, L. S.

Current software development often relies on non trivial coordination logic for combining autonomous services, eventually running on different platforms. As a rule, however, such a coordination layer is strongly weaved within the application at source code level. Therefore, its precise identification becomes a major methodological (and technical) problem and a challenge to any program understanding or refactori...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia