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The selective COX-2 inhibitor etoricoxib reduces acute inflammatory markers in ...

The selective COX-2 inhibitor Etoricoxib reduces acute inflammatory markers in a model of neurogenic laryngitis but loses its efficacy with prolonged treatment. ; OBJECTIVE: A randomised experimental study was used to evaluate the therapeutic effect of a selective cyclooxygenase-2 (COX-2) inhibitor in neurogenic laryngitis. MATERIALS AND METHODS: Male Wistar Han rats were subjected to the nasogastric intubatio...

A new model of laryngitis : neuropeptide, cyclooxygenase, and cytokine profile

Terminais nervosos na laringe : morfologia, aspectos patológicos e perspectivas...

Tese de Doutoramento Ciências da Saúde - Ciências Biológicas e Biomédicas ; Os conhecimentos actuais sobre a morfologia e a topografia dos terminais axonais sensitivos da laringe que medeiam a interacção entre irritantes no lume respiratório e o sistema nervoso e dos terminais motores responsáveis pela actividade dos músculos intrínsecos são escassos e, em alguns estudos, contraditórios. Além das funções sensi...

Distribution of neuromuscular junctions in laryngeal and syringeal muscles in v...

Vertebrates are capable of producing a variable sound spectrum. In mammals, lissamphibia, and reptiles, the larynx is the vocal organ responsible for sound production, whereas in birds it is produced by the syrinx, an avian organ located at the base of trachea. The distribution of neuromuscular junctions responsible for the fine control of laryngeal muscle (LM) and syringeal muscle (SM), although studied with s...

Intraepithelial nerve fibers project into the lumen of the larynx

Objectives/Hypothesis: Studies on the morphology and location of the sensory receptors in the laryngeal mucosa have resulted in insufficient and sometimes conflicting data. In the present study the authors analyzed the distribution and morphology of sensory nerve plexuses and terminal fibers in the laryngeal mucosa of the rat. Study Design: Two groups of Male Wistar rats were used in this laboratory study; the ...