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Exploring the osteoconductive effect of silanol groups by using human adipose s...

Rodrigues, A. I.; Gomes, Manuela E.; Leonor, I. B.; Reis, R. L.

Current methods for bone tissue engineering are concentrated in the in vitro expansion and osteogenic differentiation of stem cells since they are a key element to achieve tissue regeneration. One critical strategy for bone tissue engineering is to provide the cues necessary for guiding cell recruitment and driving tissue regeneration by mimicking the bone microenvironment. Silicon is known to have an influence...


Bioactive starch-based scaffolds and human adipose stem cells are a good combin...

Rodrigues, A. I.; Gomes, Manuela E.; Leonor, I. B.; Reis, R. L.

Silicon is known to have an influence on calcium phosphate deposition and on the differentiation of bone precursor cells. This study explores the effect of the incorporation of silanol (Si–OH) groups into poly- meric scaffolds on the osteogenic differentiation of human adipose stem cells (hASC) cultured under dynamic and static conditions. A blend of corn starch with polycaprolactone (30/70 wt.%, SPCL) was used...


Variable-temperature 1H-NMR studies on the conformations of N’-palmitoyl-rifabu...

Figueiredo, Ricardo; Duarte, Maria L.; Rodrigues, A. I.; Costa, Maria do Céu; Menezes, J. C.

Data: 2010   |   Origem: Repositório do LNEG

Ti-MCM-41 materials synthesised at room temperature as catalysts for cyclisatio...

Ramos, S.S.; Castilho, P.; Rodrigues, A.I.; Galacho, Cristina; Carrott, Manuela; Carrott, Peter

In the present work we extend the applicability of those Ti-MCM-41 materials, as heterogeneous catalysts, to produce an important intermediate, isopulegol, from the cyclisation of citronellal. The use of this kind of materials appears to be a good option over homogeneous catalysts, because they offer the advantage of recovery and, consequently, contribute to environmentally friendly processes.


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