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Money supply and the credit market in early modern economies : the case of eigh...

In this paper, we address the partial equilibrium functioning of the shortterm credit market in the Eighteenth-century Lisbon and its response to three major events: massive gold inflows from Brazil, a catastrophic destruction of capital caused by the 1755 earthquake and the enactment of a 5% legal ceiling on interest rates 1757. We build a time series for the market interest rate, and a regression shows money ...

Metodologia de Diagnóstico e Controlo de Evolução da Hepatite Aguda na Criança

Voltammetric and spectrometric determination of antioxidant capacity of selecte...

Considering the presence of phenolics in grapes and wines, as well as their importance for health promoting properties, the DPPH (1,1-diphenyl-2-picrylhidrazine) assay and a novel electroanalytical approach (differential pulse voltammetry – DPV) for analysis have been performed in order to compare the antioxidant activity of different grape beverages. A total of fifty-two wine samples from different regions aro...

Formação de subprodutos de desinfeção da água e avaliação do seu potencial geno...

Familial pseudoxanthoma elasticum with nephrocalcinosis: a case report

Pseudoxanthoma elasticum (PXE) is an autosomal recessive genetic disorder characterized by progressive calcification and fragmentation of elastic fibres. PXE commonly involves the reticular dermis, the Bruch membrane of the eye, and blood vessels. PXE is caused by mutations in the ABCC6 gene. More than 300 pathogenic ABCC6 mutations are known. Two of these mutations are common: p.R1141X in exon 24, with a preva...

Antibioterapia na Urgência: Adequabilidade de Prescrição

Antibioterapia na Urgência: Adequabilidade de Prescrição

MAN1B1 Deficiency: An Unexpected CDG-II

Congenital disorders of glycosylation (CDG) are a group of rare metabolic diseases, due to impaired protein and lipid glycosylation. In the present study, exome sequencing was used to identify MAN1B1 as the culprit gene in an unsolved CDG-II patient. Subsequently, 6 additional cases with MAN1B1-CDG were found. All individuals presented slight facial dysmorphism, psychomotor retardation and truncal obesity. Gene...

Cellular hypomethylation is associated with impaired nitric oxide production by...

Hyperhomocysteinemia (HHcy) is a risk factor for vascular disease, but the underlying mechanisms remain incompletely defined. Reduced bioavailability of nitric oxide (NO) is a principal manifestation of underlying endothelial dysfunction, which is an initial event in vascular disease. Inhibition of cellular methylation reactions by S-adenosylhomocysteine (AdoHcy), which accumulates during HHcy, has been suggest...

The monitoring of rammed earth experimental walls and characterization of ramme...

RESTAPIA 2012 - Int. Conf. on Rammed Earth Conservation, Valencia, 21-23 June 2012 ; This article analyzes differences recorded in the construction and ageing of experimental rammed earth walls. After 10-12 years of exposure some superficial degradation was observed in some walls, pointing to the necessity of applying a compatible surface protection. The behavior of samples of the rammed earth similar to those...