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Antiproliferative activity of fucan nanogel
Santos, Nednaldo Dantas; Lima, Jailma Almeida; Vidal, Arthur Anthunes Jacome; Oliveira, Ruth Medeiros; Pedrosa, Sílvia Santos; Pereira, PaulaSulfated fucans comprise families of polydisperse natural polysaccharides based on sulfated l-fucose. Our aim was to investigate whether fucan nanogel induces cell-specific responses. To that end, a non toxic fucan extracted from Spatoglossum schröederi was chemically modified by grafting hexadecylamine to the polymer hydrophilic backbone. The resulting modified material (SNFuc) formed nanosized particles. The ...
BC nanofibres : in vitro study of genotoxicity and cell proliferation
Moreira, Susana; Silva, Naisandra Bezerra; Almeida-Lima, Jailma; Rocha, Hugo Alexandre Oliveira; Medeiros, Silvia Regina BatistuzzoNanomaterials have unusual properties not found in the bulk materials, which can be exploited in numerous applications such as biosensing, electronics, scaffolds for tissue engineering, diagnostics and drug delivery. However, research in the past few years has turned up a range of potential health hazards, which has given birth to the new discipline of nanotoxicology. Bacterial cellulose (BC) is a promising mat...
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