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Urinary Estrogen Metabolites and Self-Reported Infertility in Women Infected wi...
Santos, J.; Gouveia, M.J.; Vale, N.; Delgado, M. de L.; Gonçalves, A.; da Silva, J.M.; Oliveira, C.; Xavier, P.; Gomes, P.; Santos, L.L.; Lopes, C.Schistosomiasis is a neglected tropical disease, endemic in 76 countries, that afflicts more than 240 million people. The impact of schistosomiasis on infertility may be underestimated according to recent literature. Extracts of Schistosoma haematobium include estrogen-like metabolites termed catechol-estrogens that down regulate estrogen receptors alpha and beta in estrogen responsive cells. In addition, schis...
Cardiac and vascular effects of diltiazem, dobutamine and amrinone, drugs used ...
Gómez-Alvis,A.; Rebolledo,A.; Milesi,V.; Raingo,J.; Sanz,N.; Tommasi,J.; Drago,A.; Rinaldi,G.; Grassi,A.Hemodynamic care during postoperative management of myocardial revascularization should include vasorelaxing drugs to insure adequate graft and coronary flow, and stimulation of stroke volume to maintain vascular perfusion pressure. We tested the cardiac (inotropic and lusitropic) and vascular (relaxant) effects of diltiazem (0.1 nM to 0.1 mM), dobutamine (10 µM to 10 mM) and amrinone (10 µM to 1 mM) on isolate...
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