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Dectin-1 isoforms contribute to distinct Th1/Th17 cell activation in mucosal ca...

We thank Dr. Cristina Massi Benedetti for digital art and editing ; Recognition of β-glucans by dectin-1 has been shown to mediate cell activation, cytokine production and a variety of antifungal responses. Here, we report that the functional activity of dectin-1 in mucosal immunity to Candida albicans is influenced by the genetic background of the host. Dectin-1 was required for the proper control of gastroin...