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Cumulative Mitoxantrone-Induced Haematological and Hepatic Adverse Effects in a...
Rossato, Luciana G.; Costa, Vera M.; Dallegrave, Eliane; Arbo, Marcelo; Dinis-Oliveira, Ricardo J.; Santos-Silva, Alice; Duarte, José A.Mitoxantrone (MTX) is an antineoplastic agent that can induce hepato- and haematotoxicity. This work aimed to investigate the occurrence of cumulative early and late MTX-induced hepatic and haematological disturbances in an vivo model. A control group and two groups treated with three cycles of 2.5 mg/kg MTX at days 0, 10 and 20 were formed. One of the treated groups suffered euthanasia on day 22 (MTX22) to eva...
Development framework pattern for pervasive information systems
Fernandes, José Eduardo; Machado, Ricardo J.During last decade, the world watched a social acceptance of computing and computers, enhanced information technology devices, wireless networks, and Internet; they gradually became a fundamental resource for individuals. Nowadays, people, organizations, and the environment are empowered by computing devices and systems; they depend on services offered by modern Pervasive Information Systems supported by comple...
Role of malnutrition and parasite infections in the spatial variation in childr...
Magalhães, Ricardo J. Soares; Langa, António; Pedro, João Mário; Sousa-Figueiredo, José Carlos; Clements, Archie C. A.; Nery, Susana VazAnaemia is known to have an impact on child development and mortality and is a severe public health problem in most countries in sub-Saharan Africa. We investigated the consistency between ecological and individual-level approaches to anaemia mapping by building spatial anaemia models for children aged ≤15 years using different modelling approaches. We aimed to (i) quantify the role of malnutrition, malaria, Sc...
A influência do modelo pedagógico em variáveis psicológicas de estudantes do 1º...
Teixeira, Ricardo J.; Dores, Artemisa R.; Santos, Andreia Magalhães dos; Barreto, João Francisco; Martins, HelenaIntrodução – A adaptação ao ensino superior reveste-se de experiências académicas que podem constituir fonte de stress para os estudantes. A implementação de novos modelos pedagógicos, no âmbito do processo de Bolonha, introduz novas variáveis cujo impacto, designadamente em termos de saúde, importa conhecer. Este estudo tem como objetivo analisar as associações entre modelo pedagógico (Problem Based Learning –...
Peers' evaluation of a reconfigurable IEEE1451.0-compliant and FPGA-based weblab
Costa, Ricardo J.; Alves, Gustavo R.; Zenha-Rela, Mário; Zutin, D. G.; Zackrisson, J.; Rochadel, Willian; Henandez-Jayo, UnaiIt is already more than 10 years that weblabs are seen as important resources to provide the experimental work required in engineering education. Several weblabs have been applied in engineering courses, but there are still unsolved problems related to the development of their infrastructures. For solving some of those problems, it was implemented a weblab with a reconfigurable infrastructure compliant with the...
A transformation of business process models into software-executable models usi...
Santos, Nuno A.; Duarte, Francisco J.; Machado, Ricardo J.; Fernandes, João M.Traditional software development projects for process-oriented organizations are time consuming and do not always guarantee the fulfillment of the functional requirements of the client organization, and thus the quality of the resulting software product. To reduce the time spent for developing software and improve its quality, we adopt the inclusion of automation in some parts of the software development proces...
Endocardite das válvulas das cavidades direitas: a importância da ecocardiograf...
Ricardo, J; Garcia, A; Leite, A; Serra, I; Revés, L; Miranda, C; Freitas, A; Freitas, PA endocardite das válvulas das cavidades direitas do coração é rara. Ocorre geralmente em doentes com toxicofilia endovenosa, portadores de pacemaker (PMD), portadores de próteses valvulares ou cateter venoso central e ainda em doentes com cardiopatias congénitas. A Ecocardiografia constitui o gold standard na identificação da(s) estrutura(s) afetada (s) e permite a orientação terapêutica. Apesar de ser rara, a...
Role of malnutrition and parasite infections in the spatial variation in childr...
Magalhães, Ricardo J.; Langa, António; Pedro, João Mário; Sousa-Figueiredo, J. C.; Clements, A. C.; Nery, S. V.Anaemia has a significant impact on child development and mortality and is a severe public health problem in most countries in sub-Saharan Africa. Nutritional and infectious causes of anaemia are geographically variable and anaemia maps based on information on the major aetiologies of anaemia are important for identifying communities most in need and the relative contribution of major causes. We investigated th...
Epidemiology of malaria, schistosomiasis, geohelminths, anemia and malnutrition...
Sousa-Figueiredo, José Carlos; Gamboa, Dina; Pedro, João Mário; Fançony, Cláudia; Langa, António Justino; Magalhães, Ricardo J. SoaresBackground: Malaria, schistosomiasis and geohelminth infection are linked to maternal and child morbidity and mortality in sub-Saharan Africa. Knowing the prevalence levels of these infections is vital to guide governments towards the implementation of successful and cost-effective disease control initiatives. Methodology/Principal Findings: A cross-sectional study of 1,237 preschool children (0–5 year olds), 1...
Reconfigurable IEEE1451-FPGA based weblab infrastructure
Costa, Ricardo J.; Alves, Gustavo R.; Zenha-Rela, MárioWeblabs are spreading their influence in Science and Engineering (S&E) courses providing a way to remotely conduct real experiments. Typically, they are implemented by different architectures and infrastructures supported by Instruments and Modules (I&Ms) able to be remotely controlled and observed. Besides the inexistence of a standard solution for implementing weblabs, their reconfiguration is limited to a se...
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