Encontrados 159 documentos, a visualizar página 1 de 16
Copper-driven avoidance and mortality in temperate and tropicaltadpoles
Araújo, Cristiano V.M.; Shinn, Cândida; Moreira-Santos, Matilde; Lopes, Isabel; Espíndola, Evaldo L. G.; Ribeiro, R.Amphibians have experienced an accentuated population decline in the whole world due to many factors,one of them being anthropogenic contamination. The present study aimed to assess the potential effect ofcopper, as a worldwide and reference contaminant, on the immediate decline of exposed population dueto avoidance and mortality responses in tadpoles of three species of amphibians across climatic zones:a South...
Ethoprophos fate on soil–water interface and effects on non-target terrestrial ...
Leitão, Sara; Moreira-Santos, Matilde; Van den Brink, Paul J.; Ribeiro, R.; Cerejeira, M. José; Sousa, J. P.The present study aimed to assess the environmental fate of the insecticide and nematicide ethoprophos in the soil–water interface following the pesticide application in simulated maize and potato crops under Mediterranean agricultural conditions, particularly of irrigation. Focus was given to the soil–water transfer pathways (leaching and runoff), to the pesticide transport in soil between pesticide applicatio...
The HIF1A Functional Genetic Polymorphism at Locus +1772 Associates with Progre...
Fraga, A; Ribeiro, R; Príncipe, P; Lobato, C; Pina, F; Maurício, J; Monteiro, C; Sousa, H; Calais da Silva, F; Lopes, C; Medeiros, RThe hypoxia inducible factor 1 alpha (HIF1a) is a key regulator of tumour cell response to hypoxia, orchestrating mechanisms known to be involved in cancer aggressiveness and metastatic behaviour. In this study we sought to evaluate the association of a functional genetic polymorphism in HIF1A with overall and metastatic prostate cancer (PCa) risk and with response to androgen deprivation therapy (ADT). The HIF...
The HIF1A Functional Genetic Polymorphism at Locus +1772 Associates with Progre...
Fraga, A; Ribeiro, R; Príncipe, P; Lobato, C; Pina, F; Maurício, J; Monteiro, C; Sousa, H; Calais da Silva, F; Lopes, C; Medeiros, RThe hypoxia inducible factor 1 alpha (HIF1a) is a key regulator of tumour cell response to hypoxia, orchestrating mechanisms known to be involved in cancer aggressiveness and metastatic behaviour. In this study we sought to evaluate the association of a functional genetic polymorphism in HIF1A with overall and metastatic prostate cancer (PCa) risk and with response to androgen deprivation therapy (ADT). The HIF...
Development and validation of an experimental life support system for assessing...
Coelho, Francisco J. R. C.; Rocha, Rui J. M.; Pires, Ana C. C.; Ladeiro, Bruno; Castanheira, José M.; Costa, Rodrigo; Almeida, Adelaide; Cunha, ÂngelaAn experimental life support system (ELSS) was constructed to study the interactive effects of multiple stressors on coastal and estuarine benthic communities, specifically perturbations driven by global climate change and anthropogenic environmental contamination. The ELSS allows researchers to control salinity, pH, temperature, ultraviolet radiation (UVR), tidal rhythms and exposure to selected contaminants. ...
Going with the Flow: Detection of Drift in Response to Hypo-Saline Stress by th...
Araujo, Cristiano V. M.; Romero-Romero, Sonia; Lourençato, Lucio F.; Moreno-Garrido, Ignacio; Blasco, Julián; Gretz, Michael R.; Moreira-Santos, MatildeAvoidance response is a well-known mechanism for escaping environmental stress. For organisms with reduced active movement, such as benthic microalgae, drifting could be a specifically selected mean of avoiding less favorable environments. To test this hypothesis, a system was developed to assess if hypo-saline stress triggers drift in the estuarine benthic diatom Cylindrotheca closterium. Concurrently, the eff...
Tolerance to Copper and to Salinity in Daphnia longispina: Implications within ...
Leitão, João; Ribeiro, R.; Soares, Amadeu M. V. M; Lopes, I.Considering IPPC climate change scenarios, it is pertinent to predict situations where coastal ecosystems already impacted with chemical contamination became exposed to an additional stressor under a future scenario of seawater intrusion. Accordingly, the present study aimed at evaluating if a negative association between tolerance to a metal and to saltwater exists among genotypes of a freshwater organism. For...
A laboratory and in situ postexposure feeding assay with a freshwater snail
Correia, Vânia; Ribeiro, R.; Moreira-Santos, MatildeContaminant-driven feeding inhibition has direct and immediate consequences at higher levels of biological organization, by depressing the population consumption and thus hampering ecosystem functioning (e.g., grazing, organic matter decomposition). The present study aimed at developing a short-term laboratory and in situ assay based on the postexposure feeding of the freshwater snail Theodoxus fluviatilis. A m...
Contaminant driven genetic erosion and associated hypotheses on alleles loss, r...
Ribeiro, R.; Lopes, I.Microevolution due to pollution can occur mainly through genetic drift bottlenecks, especially of small sized populations facing intense lethal pulses of contaminants, through mutations, increasing allelic diversity, and through natural selection, with the disappearance of the most sensitive genotypes. This loss of genotypes can lead to serious effects if coupled to specific hypothetical scenarios. These may be...
Could contaminant induced mutations lead to a genetic diversity overestimation?
Sobral, Olímpia; Marin-Morales, Maria Aparecida; Ribeiro, R.Contaminant driven genetic erosion reported through the inspection of selectable traits can be underestimated using neutral markers. This divergence was previously reported in the aquatic system of an abandoned pyrite mine. The most sensitive genotypes of the microcrustacean cladoceran Daphnia longispina were found to be lacking in the impacted reservoir near the entrance of the metal rich acid mine drainage (A...
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