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N-glicosilação do recetor das células t: um novo mecanismo molecular na patogén...

Early precut fistulotomy for biliary access : time to change the paradigm of "t...

Prova tipográfica ; The precut timing during the biliary cannulation algorithm is a subject of controversy. Some studies suggest that early institution of precut is a safe and effective strategy even though the extent to which this approach may affect the duration of the ERCP is seldom addressed. OBJECTIVE: To assess the success, safety, and procedure duration of an early precut fistulotomy (group A) versus a ...

Guidelines for diagnostic and treatment of gastric adenocarcinoma (Digestive Ca...

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Simulation of a Chromatic Dispersion Monitoring Scheme Using an Optical Delay-a...

A new postdetection method of dispersion is proposed, based on a scheme previously implemented, and that additionally uses a Bit Error Rate (BER) analyser, which allows the extending of the monitoring window. The monitoring method was tested with transmission rates of up to 40 Gbit/s. It showed monitoring windows of at least ± 300 ps / nm, as well as the ability to adapt to different modulation formats, ...

Gastric Cancer: An Opportunity for Prevention

Gastric cancer is one of the most prevalent cancers worldwide, ranking fourth after lung, breast and colorectal cancers, and it is the second cause of cancer death. The majority of cases occur in developing countries and are more common in males, irrespective of age and geographic area. In Portugal it ranks fifth in cancer deaths and its incidence is the highest in Western Europe.

Fat quantification in liver using chemical shift imaging

MRI is becoming increasingly important in the characterization of NAFLD, which is one of the most relevant di use liver diseases with increasing prevalence in the developed countries. Currently, biopsy is the gold standard in the early identi cation and staging of NAFLD, which is crucial to evaluate the risk of hepatocellular carcinoma development. However, the later is associated with sampling errors and with ...

Emergencies after endoscopic procedures

Endoscopy adverse events (AEs), or complications, are a rising concern on the quality of endoscopic care, given the technical advances and the crescent complexity of therapeutic procedures, over the entire gastrointestinal and bilio-prancreatic tract. In a small percentage, not established, there can be real emergency conditions, as perforation, severe bleeding, embolization or infection. Distinct variables int...

Validation of a fluorescence in situ hybridization method using peptide nucleic...

Here, we evaluated a previously established peptide nucleic acid-fluorescence in situ hybridization (PNA-FISH) method as a new diagnostic test for Helicobacter pylori clarithromycin resistance detection in paraffin-embedded gastric biopsy specimens. Both a retrospective study and a prospective cohort study were conducted to evaluate the specificity and sensitivity of a PNA-FISH method to determine H. pylori cla...

Probe4pylori : a new kit for the rapid detection of H. pylori and associated cl...

In this study an evaluation of Probe4Pylori, a previously established PNA-FISH diagnostic test for H. pylori clarithromycin resistance in paraffin embedded gastric biopsies was performed and compared against culture followed by E-test and PCR. The Probe4Pylori showed very promising results with values of sensitivity (80%) and specificity (approximately 90%) for the patients harboring clarithromycin-resistant H....

The impact of the Sentinel Node concept on the overall survival, disease-free s...

Introduction and aims: The Sentinel Node (SN) concept emerged as a way to improve Breast Cancer (BC) staging and to reduce the morbidity of the Axillary Dissection (AD). But the influence of the SN concept on long term BC outcomes is not well defined. The aim of this work is to assess the impact of the SN concept on the overall and disease-free survival and on the axillary recurrence, in a prospectively control...