Encontrados 3 documentos, a visualizar página 1 de 1
Desperdício de medicamentos no ambulatório em Portugal
Mendes, Zilda; Crisóstomo, Sofia; Marques, Francisco Batel; Martins, Ana Paula; Rodrigues, Vitor; Ribeiro, Carlos FontesResumo da comunicação apresentada à 10.ª Conferência Nacional de Economia da Saúde
Single or multiple injections of methamphetamine increased dopamine turnover bu...
Pereira, Frederico Costa; Lourenço, Elita Santos; Borges, Fernanda; Morgadinho, Teresa; Ribeiro, Carlos Fontes; Macedo, Tice Reis; Ali, Syed F.Methamphetamine (METH), leading to striatal dopamine (DA) nerve terminal toxicity in mammals, is also thought to induce apoptosis of striatal neurons in rodents. We investigated the acute effects induced by multiple injections of METH (4 × 5 mg/kg, i.p.) at 2-h intervals or a single injection of METH (20 mg/kg, i.p.) on terminal dopaminergic toxicity markers, including DA levels, DA turnover, and tyrosine hydro...
Causality assessment of adverse drug reactions: comparison of the results obtai...
Macedo, Ana Filipa; Marques, Francisco Batel; Ribeiro, Carlos Fontes; Teixeira, FredericoTo compare the results of causality assessments of reported adverse drug reactions (ADR's) obtained from decisional algorithms with those obtained from an expert panel using the WHO global introspection method (GI) and to further evaluate the influence of confounding variables on algorithms ability in assessing causality.Two hundred sequentially reported ADR's were included in this study. An independent researc...
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