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Evolution of outpatient antibiotic use in Portugal mainland 2000-2009

Introduction: In the latest years, the increasing resistance to antibiotics has become a serious public health issue. The resistance to antimicrobial agents is multifactorial although several studies have shown that the large use of antibiotics for therapeutical and prophylactic purposes, and particularly their misuse, is one factor that contributes most to this problem. Aim: To assess the evolution of antibiot...