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Hemocompatibility study of a bacterial cellulose/polyvinyl alcohol nanocomposite

Leitão, Alexandre F.; Gupta, Swati; Silva, João P.; Reviakine, I.; Gama, F. M.

Bacterial cellulose (BC) has been suggested to be a suitable biomaterial for the development of cardiovascular grafts. The combination of BC with polyvinyl alcohol (PVA) results in nanocomposites with improved properties. Surprisingly, there are very few studies on the BC–blood interaction. This is the focus of this paper. We present the first thorough assessment of the hemocompatibility of the BC/PVA nanocompo...


Hemocompatibility study of a bacterial cellulose/polyvinyl alcohol nanocomposite

Leitão, Alexandre F.; Gupta, Sanjay; Silva, João P.; Reviakine, I.; Gama, F. M.

Cardiovascular disease is among the leading causes of death in the world. Grafts are usually used to treat these diseases by redirecting blood flow around occluded vessels. We previously showed bacterial cellulose (BC) is a suitable artificial alternative to commonly used autologous grafts. We found that the addition of polyvinyl alcohol (PVA) improves the mechanical properties of BC. For cardiovascular applica...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia