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Design and characterization of a biodegradable double-layer scaffold aimed at p...

The inefficacy of the currently used therapies in achieving the regeneration ad integrum of the periodontium stimulates the search for alternative approaches, such as tissue-engineering strategies. Therefore, the core objective of this study was to develop a biodegradable double-layer scaffold for periodontal tissue engineering. The design philosophy was based on a double-layered construct obtained from a blend...

Effect of anatomical origin and cell passage number on the stemness and osteoge...

Mesenchymal stem cells have a great potential for application in cell based therapies, such as tissue engineering. Adipose derived stem cells have shown the capacity to differentiate into several lineages, and have been isolated in many animal species. Dog is a very relevant animal model to study several human diseases and simultaneously an important subject in veterinary medicine. Thus, in this study we asses...

In vitro and in vivo assessment of an innovative double layer scaffold for peri...

Canine adipose stem cells : the influence of the anatomy and passaging on the s...

Periodontal disease (PD) is an inflammatory pathology highly prevalent both in humans and in dogs, which is characterized by destruction of the periodontal ligament, cementum and alveolar bone. The development of new therapies, such as Tissue Engineering strategies, is mandatory due to the inefficacy of conventional therapies currently used. Dog is a very relevant animal model to study several human diseases, s...