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Ex vivo experimental model for percutaneous vertebroplasty: microCT utility

The aim of this study was to develop an ex vivo experimental animal model for percutaneous vertebroplasty, for further application in vivo to test novel bone injectable cements.

Gestão de armazém : caso da Plural

O seguinte relatório foi elaborado no âmbito do um estágio curricular para conclusão do Mestrado em Gestão da Faculdade de Economia da Universidade de Coimbra. O estágio foi realizado na Plural Cooperativa Farmacêutica Crl e teve a duração de dezoito semanas entre 13 de Fevereiro e 24 de Junho do atual ano. Dentro da área de Logística, foi abordado o tema de gestão de armazém, uma vez que é uma área que consome...

Stress affects theta activity in limbic networks and impairs novelty-induced ex...

Exposure to a novel environment triggers the response of several brain areas that regulate emotional behaviors. Here, we studied theta oscillations within the hippocampus (HPC)-amygdala (AMY)-medial prefrontal cortex (mPFC) network in exploration of a novel environment and subsequent familiarization through repeated exposures to that same environment; in addition, we assessed how concomitant stress exposure cou...

Chronic stress disrupts neural coherence between cortico-limbic structures

Chronic stress impairs cognitive function, namely on tasks that rely on the integrity of cortico-limbic networks. To unravel the functional impact of progressive stress in cortico-limbic networks we measured neural activity and spectral coherences between the ventral hippocampus (vHIP) and the medial prefrontal cortex (mPFC) in rats subjected to short term stress (STS) and chronic unpredictable stress (CUS). CU...

Effects of Age-Related Cognitive Deficits on EEG Phase Coherence

Body and brain undergo several changes with aging. One of these changes is the loss of neuroplasticity, which leads to the decrease of cognitive abilities. Hence the necessity of stopping or reversing these changes is of utmost importance to contemporary society. In the present work, electroencephalogram (EEG) markers of cognitive decline are sought whilst the subjects perform the Wisconsin Card Sorting Test (W...

Cognitive intervention protocol for age-related memory impairments

With the number of elderly people increasing tremendously worldwide, comes the need for effective methods to maintain or improve older adults' cognitive performance. Using continuous neurofeedback, through the use of EEG techniques, people can learn how to train and alter their brain electrical activity. A software platform that puts together the proposed rehabilitation methodology has been developed: a digital...

Chronic stress disrupts neural coherence between cortico-limbic structures

The authors would like to thank Rui Gomes for the help in the application of electrophysio- logical techniques and Luís Martins and Miguel Carneiro for the histological preparations. ; Chronic stress impairs cognitive function, namely on tasks that rely on the integrity of cortico-limbic networks. To unravel the functional impact of progressive stress in cortico-limbic networks we measured neural activity and ...

Stress affects theta activity in limbic networks and impairs novelty-induced ex...

Exposure to a novel environment triggers the response of several brain areas that regulate emotional behaviors. Here, we studied theta oscillations within the hippocampus (HPC)-amygdala (AMY)-medial prefrontal cortex (mPFC) network in exploration of a novel environment and subsequent familiarization through repeated exposures to that same environment; in addition, we assessed how concomitant stress exposure cou...

A dissociação experimental de N1 e P2: dois componentes distintos do potencial ...

Atividade física : um complemento a considerar no tratamento da depressão

Introdução: A Depressão é uma psicopatologia multifatorial, incapacitante e com elevados custos económicos e emocionais, cuja etiologia ainda não está totalmente esclarecida. A sua incidência tem aumentado ao longo das últimas décadas e apesar das estratégias utilizadas no seu tratamento, nomeadamente a farmacoterapia e a psicoterapia, as recaídas são elevadas e as taxas de remissão são baixas. Com o intuito de...