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Dynamic culture of osteogenic cells in biomimetically coated poly(caprolactone)...
Araújo, J. V.; Reis, C. Cunha; Rada, Tommaso; Silva, Marta Alves da; Gomes, Manuela E.; Yang, Y.; Ashammakhi, N.; Reis, R. L.; El-Haj, Alicia J.In our previous work, biomimetic calcium phosphate-coated poly(caprolactone) nanofibre meshes (BCP-NMs) were demonstrated to be more effective for supporting cell attachment and proliferation under static conditions, when compared with poly(caprolactone) nanofibre meshes (PCL-NMs). In many applications, in vitro cultivation of constructs using bioreactors that support efficient nutrition of cells has appeared a...
Influence of porosity and fibre diameter on the degradation of chitosan fibre-m...
Reis, C. Cunha; Tuzlakoglu, K.; Baas, E.; Yang, Y.; El Haj, A.; Reis, R. L.The state of the art approaches for tailoring the degradation of chitosan scaffolds are based on altering the chemical structure of the polymer. Nevertheless, such alterations may lead to changes in other properties of scaffolds, such as the ability to promote cell adhesion. The aim of this study was to investigate the influence of physical parameters such as porosity and fibre diameter on the degradation of ch...
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