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Retinal function in best macular dystrophy: relationship between electrophysiol...
Maia-Lopes, Susana; Silva, Eduardo Duarte; Reis, Aldina; Silva, Maria Fátima; Mateus, Catarina; Castelo-Branco, MiguelPURPOSE: To establish structure-function correlations across the visual field, to investigate disease progression in Best macular dystrophy (BMD), by correlating structural damage with retinal function as assessed by the combination of psychophysics and multifocal electrophysiology. METHODS: Spatial achromatic and chromatic contrast sensitivities (probing red-green and blue-yellow pathways) were assessed using ...
Evidence of widespread retinal dysfunction in patients with stargardt disease a...
Maia-Lopes, Susana; Silva, Eduardo D.; Silva, Maria Fátima; Reis, Aldina; Faria, Pedro; Castelo-Branco, MiguelPURPOSE: To characterize contrast sensitivity (CS) across the visual field for two achromatic spatial-temporal frequencies in 21 families with Stargardt disease (STGD) and to correlate psychophysical impairment with patterns of change in multifocal electroretinography (mfERG). METHODS: Twenty-seven eyes from patients with STGD, 16 eyes from asymptomatic relatives, and 44 age-matched control eyes were included. ...
Breakdown of the Inner and Outer Blood Retinal Barrier in Streptozotocin-Induce...
Carmo, Anália do; Ramos, Pedro; Reis, Aldina; Proença, Rui; Cunha-Vaz, J. G.Using vitreous fluorophotometry and quantitative fluorescence microscopy the authors studied the permeability of the blood-retinal barrier (BRB) to fluorescein in control and in 8 days streptozotocin-induced diabetic rats. ; http://www.sciencedirect.com/science/article/B6WFD-45JC7TK-T/1/ad834a7e41da87410003af7710548c3d
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