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Cost-effectiveness of trastuzumab in the treatment of early stages breast cance...

Macedo, Ana; Monteiro, Isabel; Andrade, Sofia; Cirrincione, A; Ray, J

Despite the important advances observed in the last 25 years in the comprehension of the clinical and biological nature of breast cancer and its treatment, this disease remains a significant cause of cancer morbidity and mortality worldwide. The clinical trial Hera has demonstrated the safety and efficacy of trastuzumab in the treatment of HER2 positive (HER2+) breast cancer patients, in early stages, subsequen...

Data: 2010   |   Origem: Acta Médica Portuguesa

Photorefractive keratectomy for moderate myopia with the VISX and Summit excime...

Ribeiro,João C.; Ancel,Jean M.; McDonald,Marguerite B.; Varnell,Ray J.

Purpose: To present photorefractive keratectomy (PRK) results for myopia ranging from -4,00 to - 6,00 diopters performed with the VISX and Summit excimer lasers. Methods: To be eligible for this study, patients had to be 20 to 45 years of age, have -4.00 to -6.00 diopters of myopia and have no more than 1 D of astigmatism. The Summit group was composed of 51 eyes. The baseline preoperative spherical equivalent ...

Data: 2000   |   Origem: OASIS br

The use of mini-projects in an undergraduate laboratory course in chemistry

Vianna,José F.; Sleet,Ray J.; Johnstone,Alex H.

This paper reports the results of a three-year study of the effectiveness of mini-projects in a first year laboratory course in chemistry at a Scottish university. A mini-project is a short, practical problem which requires for its solution the application of the knowledge and skills developed in previously completed set experiments. A number of recommendations have been made about the most appropriate ways of ...

Data: 1999   |   Origem: OASIS br

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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia