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Pharmaceutical topical dosage forms as carriers for glucocorticoids

Raposo, Sara Sofia Caliço, 1984-

Tese de doutoramento, Farmácia (Tecnologia Farmacêutica), Universidade de Lisboa, Faculdade de Farmácia, 2013 ; With rapid developments in materials science, pharmaceutics and biotechnology, new systems have emerged for topical glucocorticoids delivery. Despite being a mature class of drugs, they are still the most frequently prescribed drugs by dermatologists, explaining the interest on this field. Over the y...


Um Estudo sobre Consumo de Derivados de Cannabis Sativa pelos Adolescentes do E...

Raposo, Sara; Sousa, Áurea; Pereira, Hélder Rocha

XIX Jornadas de Classificação e Análise de Dados (JOCLAD2012). Março 28 - 31, 2012, Tomar, Portugal (Comunicação). ; A Cannabis sativa é a droga ilícita mais produzida e consumida na Europa, podendo ser considerada como "porta de entrada" para o consumo de outras drogas ilícitas. Embora seja uma "droga leve", é reconhecido o seu impacto nas alterações de memória, nas sensações e nos comportamentos. Neste traba...


Mixing efficiency on plant cell growth and proteinase production in a stirred t...

Raposo, Sara; Lima-Costa, Maria Emília

Mixing efficiency is one of the most significant factors in bioprocess productivity. The major role of agitation is to improve broth homogenization, mass and heat transfer inside the bioreactors.


The performance of an aerated stirred tank reactor on VHG batch fermentations

Raposo, Sara; Lima-Costa, Maria Emília; Rodrigues, B.

The quest for new and renewable energy sources has greatly increased due to the depletion of fossil fuels reserves. Agro-food wastes appear as a cheap and renewable energy source that can contain great amounts of carbon to be transformed in bioethanol that can be used as additive to gasoline.


Effect of oxygen carriers in microbial and plant cell cultures.

Raposo, Sara; Santos, M.

Dissolved oxygen concentration is one of the most limiting factors in aerobic cultures, due to the poor solubility of oxygen in aqueous media. In many processes, the microorganisms growth and production can be affected as a result of insufficient oxygen supply to the broths [1, 2]. To increase oxygen solubility, some methods can be used, such as the increment of aeration or agitation rates or decrease of the...


Hydrolysis of lignocellulosic material of carob pulp in Batch, SSF and NSSF pro...

Raposo, Sara; Tavares, C.; Rodrigues, B.; Caiado, D.; Lima-Costa, Maria Emília

The progress of technologies for fuel ethanol production is a priority, because this biofuel is one of the most important resources used as renewable energy sources.


Production of bioethanol from sweet potato, agro industrial wastes

Raposo, Sara; Marques, L.; Tavares, C.; Duarte, C.; Lima-Costa, Maria Emília

One fraction of the existent petroleum is not extractable or the difficulties associated to extraction are very expensive making them unviable. This situation leads to a decrease in petroleum stocks all over the world and a resulting increment on its price, affecting in particular the transportation sector, since there is no relevant alternative to fossil petroleum.


Cost-effective bioethanol production at low content of nitrogen source from car...

Raposo, Sara; Tavares, C.; Rodrigues, B.; Lima-Costa, Maria Emília; Quintas, Célia; Rodrigues, F.

Ethanol, as biofuel, has received great interest in the latest decades due to its potential as an alternative transport fuel. Nowadays, ethanol can be produced through fermentative processes, using sugar rich agricultural raw material and it may have a significant role in reducing environmental impact of fossil fuels.


Development of an empirical correlation for Newtonian and non-Newtonian fluids ...

Raposo, Sara; Azevedo, F.; Lima-Costa, Maria Emília

Most of animal and plant cell cultures present a non-Newtonian behaviour that has a deep effect on the technological performance of bioreactors, affecting the pattern of mixing, the power input required and on the mass and energy transfer as well. In aerobic cultures, the oxygen mass transfer is still a bottleneck, particularly at industrial scale-up, where the high-cell-density biomass and production of metabo...


Sustainable bioethanol production using agro-industrial by-products

Pardão, J. M.; Diaz, I.; Raposo, Sara; Manso, Teresa; Lima-Costa, Maria Emília

This work aimed to evaluate a sustainable bioethanol production by a laboratorial isolate strain of Saccharomyces cerevisiae, along with the use of agro-industrial by-products as carbon source. The effect of several carbon sources and their concentrations was studied using carob pod extract (CPE) and beet molasses (BM) and compared with glucose and sucrose as conventional carbohydrates at different concentra...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia