Tese de doutoramento, Farmácia (Tecnologia Farmacêutica), Universidade de Lisboa, Faculdade de Farmácia, 2013 ; With rapid developments in materials science, pharmaceutics and biotechnology, new systems have emerged for topical glucocorticoids delivery. Despite being a mature class of drugs, they are still the most frequently prescribed drugs by dermatologists, explaining the interest on this field. Over the y...
XIX Jornadas de Classificação e Análise de Dados (JOCLAD2012). Março 28 - 31, 2012, Tomar, Portugal (Comunicação). ; A Cannabis sativa é a droga ilícita mais produzida e consumida na Europa, podendo ser considerada como "porta de entrada" para o consumo de outras drogas ilícitas. Embora seja uma "droga leve", é reconhecido o seu impacto nas alterações de memória, nas sensações e nos comportamentos. Neste traba...
Mixing efficiency is one of the most significant factors in bioprocess productivity. The major role of agitation is to improve broth homogenization, mass and heat transfer inside the bioreactors.
The quest for new and renewable energy sources has greatly increased due to the depletion of fossil fuels reserves. Agro-food wastes appear as a cheap and renewable energy source that can contain great amounts of carbon to be transformed in bioethanol that can be used as additive to gasoline.
Dissolved oxygen concentration is one of the most limiting factors in aerobic cultures, due to the poor solubility of oxygen in aqueous media. In many processes, the microorganisms growth and production can be affected as a result of insufficient oxygen supply to the broths [1, 2]. To increase oxygen solubility, some methods can be used, such as the increment of aeration or agitation rates or decrease of the...
The progress of technologies for fuel ethanol production is a priority, because this biofuel is one of the most important resources used as renewable energy sources.
One fraction of the existent petroleum is not extractable or the difficulties associated to extraction are very expensive making them unviable. This situation leads to a decrease in petroleum stocks all over the world and a resulting increment on its price, affecting in particular the transportation sector, since there is no relevant alternative to fossil petroleum.
Ethanol, as biofuel, has received great interest in the latest decades due to its potential as an alternative transport fuel. Nowadays, ethanol can be produced through fermentative processes, using sugar rich agricultural raw material and it may have a significant role in reducing environmental impact of fossil fuels.
Most of animal and plant cell cultures present a non-Newtonian behaviour that has a deep effect on the technological performance of bioreactors, affecting the pattern of mixing, the power input required and on the mass and energy transfer as well. In aerobic cultures, the oxygen mass transfer is still a bottleneck, particularly at industrial scale-up, where the high-cell-density biomass and production of metabo...
This work aimed to evaluate a sustainable bioethanol production by a laboratorial isolate strain of Saccharomyces cerevisiae, along with the use of agro-industrial by-products as carbon source. The effect of several carbon sources and their concentrations was studied using carob pod extract (CPE) and beet molasses (BM) and compared with glucose and sucrose as conventional carbohydrates at different concentra...
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