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Establishment of an in vivo model of human hematopoiesis on a three-dimensional...

Umbilical cord blood hematopoietic stem cell transplantation (UCB-HSCT) is an increasing area both clinical and translational investigation. The main hurdle of this approach is a delayed engraftment (or even a graft failure) that accounts the most of the transplantrelated mortality. To gain insight on the factors that may influence UCB engraftment is important to implement the clinical procedure. The interactio...