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Avaliação da Sobrevivência e do Desenvolvimento Psicomotor em Ex-Recém- Nascido...

Objectivos: Estudo da sobrevivência do Recém Nascido de Muito Baixo Peso (RNMBP) ao longo de 11 anos (1987 a 1997) e avaliação do desenvolvimento psicomotor das crianças com idade igual ou superior a três anos de idade, nascidas em dois períodos diferentes, com práticas diferentes no seu cuidar.Metodologia: Determinou-se a taxa de sobrevivência de 262 e 159 RNMBP nascidos, respectivamente, entre 1987-1993 (perí...

Novas ferramentas de apoio na limitação da praga Tuta absoluta na cultura de ...

traça do tomateiro, Tuta absoluta, é, atualmente, praga-chave de tomate para indústria, no Ribatejo. Detetou-se a sua presença nesta cultura em 2010, tendo causado prejuízos significativos na campanha de 2011. Durante o ano 2013 efetuaram-se, semanalmente, monitorização de adultos com armadilhas com feromona sexual e observações visuais em 25 a 50 plantas, de acordo com o estado fenológico da cultura....

Vigilância laboratorial das infeções por Neisseria gonorrhoeae em Portugal, 200...

Eigenvalue computations in the context of data-sparse approximations of integra...

In this work, we consider the numerical solution of a large eigenvalue problem resulting from a finite rank discretization of an integral operator. We are interested in computing a few eigenpairs, with an iterative method, so a matrix representation that allows for fast matrix-vector products is required. Hierarchical matrices are appropriate for this setting, and also provide cheap LU decompositions required i...

Error bounds for low-rank approximations of the first exponential integral kernel

A hierarchical matrix is an efficient data-sparse representation of a matrix, especially useful for large dimensional problems. It consists of low-rank subblocks leading to low memory requirements as well as inexpensive computational costs. In this work, we discuss the use of the hierarchical matrix technique in the numerical solution of a large scale eigenvalue problem arising from a finite rank discretization...

Avaliação nutricional de uma população de doentes renais crónicos a realizar di...

[Abstract] ; [Resumo]

Evidence for eosinophil recruitment, leukotriene B4 production and mast cell hy...

It is well known that eosinophilia is a key pathogenetic component of toxocariasis. The objective of the present study was to determine if there is an association between peritoneal and blood eosinophil influx, mast cell hyperplasia and leukotriene B4 (LTB4) production after Toxocara canis infection. Oral inoculation of 56-day-old Wistar rats (N = 5-7 per group) with 1000 embryonated eggs containing third-stage...

Transcriptomic analysis of plasmid and plasmid-related chromosomal ORFs in C. t...

Despite the undergoing chromosomal size-reduction of Chlamydia trachomatis, almost all strains maintain the conserved 7,5kb plasmid. It has been recently considered a virulence factor, as plasmid-bearing strains evidenced a higher ability to successfully colonize epithelial cells and sustain infection than plasmidless strains. However, the biological role of the eight plasmid ORFs remains poorly characterized. ...

Normalization strategies for real-time expression data in Chlamydia trachomatis

Since Chlamydia trachomatis is a genetically non-tractable pathogen, transcriptomics assumes a fundamental role for the better understanding of its biology. However, the suitability of endogenous controls for normalization of transcriptomic data in this bacterium still needs validation. We aimed to assess the stability of 10 genes for their potential use as endogenous controls in qPCR at both normal and stress ...

Molecular features underlying the higher ecological success of C. trachomatis E...

In the light of the >98% genomic similarity among Chlamydia trachomatis serovars, the higher worldwide ecological success of E and F is enigmatic. We intend to provide a quick overview of the molecular data that distinguish these from the remaining strains. Examples are: - E and F possess a similar chromosomal genetic make-up distinct from the remaining genotypes. Some loci linked to this independent co-segrega...