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Predictive Variables Affecting Transfusion Requirements in Orthotopic Liver Tra...
Araújo, T; Cordeiro, A; Proença, P; Perdigoto, R; Martins, A; Barroso, EINTRODUCTION AND AIMS: Adult orthotopic liver transplantation (OLT) is associated with considerable blood product requirements. The aim of this study was to assess the ability of preoperative information to predict intraoperative red blood cell (RBC) transfusion requirements among adult liver recipients. METHODS: Preoperative variables with previously demonstrated relationships to intraoperative RBC transfusio...
Host- and microbe-related risk factors for and pathophysiology of fatal Rickett...
Sousa, R; França, A; Nóbrega, SD; Belo, A; Amaro, M; Abreu, T; Poças, J; Proença, P; Vaz, J; Torgal, J; Bacellar, F; Ismail, N; Walker, DBACKGROUND: The pathophysiologic mechanisms that determine the severity of Mediterranean spotted fever (MSF) and the host-related and microbe-related risk factors for a fatal outcome are incompletely understood. METHODS: This prospective study used univariate and multivariate analyses to determine the risk factors for a fatal outcome for 140 patients with Rickettsia conorii infection admitted to 13 Portuguese h...
A fatal forensic intoxication with fenarimol: analysis by HPLC/DAD/MSD
Proença, P.; Marques, E. Pinho; Teixeira, H.; Castanheira, F.; Barroso, M.; Ávila, S.; Vieira, D. N.Fenarimol (Rubigan®) is a pyrimidine ergosterol biosynthesis inhibitor used as a systemic fungicide. The authors present a fatal fenarimol intoxication case analysed in the Forensic Toxicology Service of the National Institute of Legal Medicine. The results were used to compare two different HPLC techniques, regarding selectivity and sensitivity: an HPLC system with a diode array detector (DAD) and an HPLC syst...
Analytical method for the determination of strychnine in tissues by gas chromat...
Marques, E. P.; Gil, F.; Proença, P.; Monsanto, P.; Oliveira, M. F.; Castanheira, A.; Vieira, D. N.This paper describes an analytical method for strychnine determination in biological samples by gas chromatography/mass spectrometry and their application in the investigation of two cases involving strychnine ingestion: A fatal case and a clinical one. The strychnine is isolated from biological samples using a liquid-liquid extraction procedure. The clean-up procedure is performed using an acid solution. Papav...
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