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Interaction of S413-PV cell penetrating peptide with model membranes: relevance...
Mano, Miguel; Henriques, Ana; Paiva, Artur; Prieto, Manuel; Gavilanes, Francisco; Simões, Sérgio; Lima, Maria C. Pedroso DeCell penetrating peptides (CPPs) have been successfully used to mediate the intracellular delivery of a wide variety of molecules of pharmacological interest both in vitro and in vivo, although the mechanisms by which the cellular uptake occurs remain unclear and controversial. Following our previous work demonstrating that the cellular uptake of the S413-PV CPP occurs mainly through an endocytosis-independent ...
Ciprofloxacin interactions with bacterial protein OmpF: Modelling of FRET from ...
Fernandes, Fábio; Neves, Patrícia; Gameiro, Paula; Loura, Luís M. S.; Prieto, ManuelThe outer membrane protein F (OmpF) is known to play an important role in the uptake of fluoroquinolone antibiotics by bacteria. In this study, the degree of binding of the fluoroquinolone antibiotic ciprofloxacin to OmpF in a lipid membrane environment is quantified using a methodology based on Förster resonance energy transfer (FRET). Analysis of the fluorescence quenching of OmpF is complex as each OmpF mono...
The 9-antroate chromophore as a fluorescence probe for water
Costa, Fernando Pestana da; Costa, Sílvia B.; Melo, Eurico C.; Prieto, Manuel; Maçanita, AntónioXI IUPAC Symposium on Photochemistry, realizado em Lisboa, na Fundação Calouste Gulbenkian de 27 de Julho a 1 de Agosto de 1986
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