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Relationships between transcription, silver staining and chromatin organization...
Caperta, A.; Neves, Nuno; Viegas, Wanda; Pikaard, Craig S.; Preuss, SashaSummary. The nucleolar organizer regions (NORs) are composed of hundreds of rRNA genes, typically spanning several megabases. Cytologically, NORs include regions that are highly condensed and regions that are decondensed, the latter corresponding to regions at which associated proteins stain intensively with silver (Ag-NORs) and where active rRNA gene transcription is thought to occur. To test the relationship ...
Postembryonic establishment of megabase-scale gene silencing in nucleolar domin...
Silva, Manuela; Viegas, Wanda; Pontes, Olga; Lawrence, Richard; Preuss, Sasha; Costa-Nunes, Pedro; Earley, Keith; Neves, Nuno; Pikaard, CraigNucleolar dominance is an epigenetic phenomenon in plant and animal genetic hybrids that describes the expression of 45S ribosomal RNA genes (rRNA genes) inherited from only one progenitor due to the silencing of the other progenitor’s rRNA genes. rRNA genes are tandemly arrayed at nucleolus organizer regions (NORs) that span millions of basepairs, thus gene silencing in nucleolar dominance occurs on a scale se...
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