Encontrados 2 documentos, a visualizar página 1 de 1
Exercise attenuates levodopa-induced dyskinesia in 6-hydroxydopamine-lesioned mice
Jr., A. S. Aguiar; Moreira, E. L. G.; Hoeller, A. A.; Oliveira, P. A.; Córdova, F. M.; Glaser, V.; Walz, R.; Cunha, R. A.; Leal, R. B.; Latini, A.l-DOPA alleviates the motor symptoms of Parkinson’s disease, but its long-term use is associated with undesirable dyskinesia. We now tested whether exercise can attenuate this l-DOPA-induced dyskinesia (LID). We tested the effects of exercise on LID in 6-hydroxydopamine hydrochloride-hemiparkinsonian mice. Animals were treated with l-DOPA/benserazide (25/12.5 mg/kg, i.p.) without and with possibility to exercis...
Spatial memory impairments in a prediabetic rat model
Soares, E.; Prediger, R. D.; Nunes, S.; Castro, A. A.; Viana, S .D.; Lemos, C.; Souza, C. M. De; Agostinho, P.; Cunha, R. A.; Carvalho, E.Diabetes is associated with an increased risk for brain disorders, namely cognitive impairments associated with hippocampal dysfunction underlying diabetic encephalopathy. However, the impact of a prediabetic state on cognitive function is unknown. Therefore, we now investigated whether spatial learning and memory deficits and the underlying hippocampal dysfunction were already present in a prediabetic animal m...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||