Encontrados 46 documentos, a visualizar página 1 de 5
Functional modifications associated with gastrointestinal tract organogenesis d...
Gomes, Ana S.; Kamisaka, Y.; Harboe, Torstein; Power, Deborah; Rønnestad, I.Background: Flatfish metamorphosis is a hormone regulated post-embryonic developmental event that transforms a symmetric larva into an asymmetric juvenile. In altricial-gastric teleost fish, differentiation of the stomach takes place after the onset of first feeding, and during metamorphosis dramatic molecular and morphological modifications of the gastrointestinal (GI-) tract occur. Here we present the functio...
Nematode and Arthropod Genomes Provide New Insights into the Evolution of Class...
Cardoso, J. C. R.; Félix, Rute C.; Power, DeborahNematodes and arthropods are the most speciose animal groups and possess Class 2 B1 G-protein coupled receptors (GPCRs). Existing models of invertebrate Class 2 B1 GPCR evolution are mainly centered on Caenorhabditis elegans and Drosophila melanogaster and a few other nematode and arthropod representatives. The present study reevaluates the evolution of metazoan Class 2 B1 GPCRs and orthologues by exploring the...
Polar marine biology science in Portugal and Spain: Recent advances and future ...
Xavier, José C.; Barbosa, Andrés; Agustí, Susana; Alonso-Sáez, Laura; Alvito, Pedro; Ameneiro, Julia; Ávila, Conxita; Baeta, Alexandra; Canário, JoãoPolar marine ecosystems have global ecological and economic importance because of their unique biodiversity and their major role in climate processes and commercial fisheries, among others. Portugal and Spain have been highly active in a wide range of disciplines in marine biology of the Antarctic and the Arctic. The main aim of this paper is to provide a synopsis of some of the results and initiatives undertak...
Adaptation to different salinities exposes functional specialization in the int...
Gregório, SÃlvia F.; Carvalho, Edison Samir Mascarelhas; Encarnação, Sandra; Wilson, J.; Power, Deborah; Canario, Adelino V. M.; Fuentes, J.The processing of intestinal fluid, in addition to a high drinking rate, is essential for osmoregulation in marine fish. This study analyzed the long-term response of the sea bream (Sparus aurata L.) to relevant changes of external salinity (12, 35 and 55ï€ p.p.t.), focusing on the anterior intestine and in the less-often studied rectum. Intestinal water absorption, epithelial HCO3– secretion and gene express...
Identification of molecular and physiological responses to chronic environmenta...
Clark, M. S.; Thorne, Michael A. S.; Amaral, Ana; Vieira, Florbela; Batista, Frederíco M.; Reis, João; Power, DeborahUnderstanding the environmental responses of an invasive species is critical in predicting how ecosystem composition may be transformed in the future, especially under climate change. In this study, Crassostrea gigas, a species well adapted to the highly variable intertidal environment, was exposed to the chronic environmental challenges of temperature (19 and 24°C) and pH (ambient seawater and a reduction of 0...
Functional characterization and evolution ofPTH/PTHrP receptors: insights from ...
Pinheiro, Pedro L. C.; Cardoso, João; Power, Deborah; Canario, Adelino V. M.The parathyroid hormone (PTH)-family consists of a group of structurally related factors that regulate calcium and bone homeostasis and are also involved in development of organs such as the heart, mammary gland and immune system. They interact with specific members of family 2 B1 G-protein coupled receptors (GPCRs), which have been characterised in teleosts and mammals. Two PTH/PTHrP receptors, PTH1R and PTH2R...
Sample richness and genetic diversity as drivers of chimera formation in nSSU m...
Fonseca, V. G.; Nichols, B.; Lallias, D.; Quince, C.; Carvalho, G .R.; Power, Deborah; Creer, S.Eukaryotic diversity in environmental samples is often assessed via PCR-based amplification of nSSU genes. However, estimates of diversity derived from pyrosequencing environmental data sets are often inflated, mainly because of the formation of chimeric sequences during PCR amplification. Chimeras are hybrid products composed of distinct parental sequences that can lead to the misinterpretation of diversity es...
Feeding and the rhodopsin family g-protein coupled receptors in nematodes and a...
Cardoso, J. C. R.; Félix, Rute C.; Fonseca, Vera G.; Power, DeborahIn vertebrates, receptors of the rhodopsin G-protein coupled superfamily (GPCRs) play an important role in the regulation of feeding and energy homeostasis and are activated by peptide hormones produced in the brain-gut axis.These peptides regulate appetite and energy expenditure by promoting or inhibiting food intake. Sequence and function homologs of human GPCRs involved in feeding exist in the nematode round...
Prolactin regulates luminal bicarbonate secretion in the intestine of the sea b...
Ferlazzo, A.; Carvalho, E. S. M.; Gregorio, S. F.; Power, Deborah; Canario, Adelino V. M.; Tischitta, F.; Fuentes, J.The pituitary hormone prolactin is a pleiotropic endocrine factor that plays a major role in the regulation of ion balance in fish, with demonstrated actions mainly in the gills and kidney. The role of prolactin in intestinal ion transport remains little studied. In marine fish, which have high drinking rates, epithelial bicarbonate secretion in the intestine produces luminal carbonate aggregates believed to pl...
Skin healing and scale regeneration in fed and unfed sea bream, Sparus auratus
Vieira, Florbela A.; Gregório, Sílvia F.; Ferraresso, Serena; Thorne, Michael A. S.; Costa, Rita; Milan, Massimo; Bargelloni, Luca; Clark, M. S.Abstract Background Fish scales are an important reservoir of calcium and phosphorus and together with the skin function as an integrated barrier against environmental changes and external aggressors. Histological studies have revealed that the skin and scales regenerate rapidly in fish when they are lost or damaged. In the present manuscript the histological and molecular changes underlying skin and scale rege...
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