The inflammatory cytokines interleukin-1\u2424 and tumor necrosis factor-\u2423 (TNF-\u2423) have been identified as mediators of several forms of neurodegeneration in the brain. However, they can produce either deleterious or beneficial effects on neuronal function. We investigated the effects of these cytokines on neuronal death caused by exposure of mouse organotypic hippocampal slice cultures to toxic conce...
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