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Chondrogenic potential of injectable K-carrageenan hydrogel with encapsulated a...

Due to the limited self-repair capacity of cartilage, regenerative medicine therapies for the treatment of cartilage defects must use a significant amount of cells, preferably applied using a hydrogel system that can promise their delivery and functionality at the specific site. This paper discusses the potential use of k-carrageenan hydrogels for the delivery of stem cells obtained from adipose tissue in the t...

Cryopreservation of cell laden natural origin hydrogels for cartilage regenerat...

The time span needed for obtaining a functional cartilage substitute using tissue engineering strategies, together with the need for specific patient oriented constructs has stimulated the growing interest for developing “off-the shelf” products. One way to deliver such products is based on long-term storage processes, such as cryopreservation, that will provide the clinical substitute available as needed and c...

An investigation of the potential application of chitosan/aloe-based membranes ...

A significant number of therapeutics derived from natural polymers and plants have been developed to replace or to be used in conjunction with existing dressing products. The use of the therapeutic properties of aloe vera could be very useful in the creation of active wound dressing materials. The present work was undertaken to examine issues concerning structural features, topography, enzymatic degradation beh...

Silk hydrogels from non-mulberry and mulberry silkworm cocoons processed with i...

Matrices based on silk fibroin from the non-mulberry silkworm Antheraea mylitta and the mulberry silkworm Bombyx mori have demonstrated good applicability in regenerative medicine. However, the cocoons of A. mylitta are underutilized in part due to their lack of solubility in traditional organic solvents. Therefore, the present work investigates the solubilization and processing of degummed fibers obtained from...

Magnetic-responsive hydrogels for cartilage tissue engineering

Publicado em "Journal of Tissue Engineering and Regenerative Medicine", vol. 7, supp. 1 (2013) ; The use of magnetic nanoparticles (MNPs) has been explored as an alternative approach to overcome current limitations of regenerative medicine strategies. Cell engineering approaches where MNPs are incorporated within three-dimensional constructs, such as scaffolds or hydrogels may constitute a novel and attractive...

Combination of aloe vera improves the biological performance of chitosan membra...

Publicado em "Journal of Tissue Engineering and Regenerative Medicine", vol. 7, suppl. 1 (2013) ; In the last years, aloe vera (AV), a tropical plant belonging to theliliaceaefamily, has gained popularity for medical, cosmetic and nutritional purposes. Commercially, AV appears in food supplements, as additive to drinks, coating fruits, moisturizer, and healing agent in cosmetic products, among others uses. The...

Chondrogenic phenotype of different cells encapsulated in κ-carrageenan hydroge...

Engineering articular cartilage substitutes using hydrogels with encapsulated cells is an approach that has received increasing attention in recent years. Hydrogels based on κ-carrageenan (κC), a thermoreversible natural-origin polymer, have been recently proposed as new cell/growth factor delivery vehicles for regenerative medicine. In this work, we report the potential of such hydrogels encapsulating either h...

Cell encapsulation system using beads and fibres from natural origin polymers f...

Novel hydrogels based on carrageenan with encapsulated adipose derived stem cel...

Designing silk fibroin-based matrices with ionic liquids for tissue engineering...

Silk (SF) is an attractive biomaterial to be used in tissue engineering applications because of its excellent mechanical properties and biocompatibility [1, 2]. In this work, the cellular response of silk hydrogels produced through dissolution of this protein in ionic liquids (ILs) was investigated. For that, degummed fibers obtained from the cocoons of mulberry silkworm (Bombyx mori) were dissolved in an IL an...