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Chemical ecology of echinoderms : impact of environment and diet in metabolomic...

Pereira, David M.; Andrade, Paula B.; Pires, R. A.; Reis, R. L.

The phylum Echinodermata constitutes a successful and widespread group comprising Asteroidea, Ophiuroidea, Echinoidea, Holothuroidea and Crinodeia. Nowadays, marine organisms are being given a lot of attention in drug discovery pipelines. In these studies, sponges and nudibranchs are frequently addressed, however an increasing number of works focus their attention in echinoderms. Given the fact that many of the...


Técnicas de Anestesia Regional em Cirurgia Ortopédica Pediátrica - Estudo Retro...

Carneiro, A; Rodrigues, A; Trindade, H; Pires, R

A anestesia regional em ortopedia apresenta vantagens claras na estabilidade hemodinâmica, perfusão do território cirúrgico e analgesia de qualidade superior. o objectivo deste estudo foi avaliar o tipo e frequência de técnicas realizadas no ano de 2012 em anestesia para cirurgia ortopédica pediátrica. Um total de 662 crianças agendadas para cirurgia electiva foram retrospectivamente estudadas no que diz respei...


Tailor made degradable ureteral stents from natural origin polysaccharides

Barros, Alexandre A.; Duarte, Ana Rita C.; Pires, R. A.; Lima, Estêvão Augusto Rodrigues de; Mano, J. F.; Reis, R. L.

A urinary stent is defined as a thin tube, which is inserted in the ureter to prevent or treat the obstruction of urine flow from the kidney. Silicone, latex, polyvinylchloride and polyurethanes are the most widely used materials for the preparation of stents. Nonetheless, severe clinical complications may result from the use of these materials such as fracture, encrustation and infection. In some of the cases,...


Immobilization of bioactive factor-loaded liposomes at the surface of electrosp...

Monteiro, Nelson; Martins, Albino; Pires, R. A.; Faria, Susana, 1972-; Fonseca, Nuno A.; Moreira, João N.; Reis, R. L.; Neves, N. M.

Publicado em "Journal of Tissue Engineering and Regenerative Medicine", vol. 7, supp. 1 (2013) ; The ability to manipulate and control the surface properties is of crucial importance in the designing of scaffolds for Tissue Engineering (TE) and Regenerative Medicine. Electrospun nanofibers (NFM), due to their morphology and fibrous structure have received much attention as potential biomedical devices, TE scaf...


Sulfonic groups induce formation of filopodia in mesenchymal stem cells

Costa, Diana Soares da; Pires, R. A.; Frias, A. M.; Reis, R. L.; Pashkuleva, I.

Glycosaminoglycans (GAGs) are an integral part of the extracellular matrix and glycocalix, i.e. the closest cellular environment. They are abundant in –OH groups and their bioactivity is also associated with the presence of negatively charged –SO3H functionalities. Therefore, we have investigated and discussed the influence of these functional units on mesenchymal stem cells (MSCs) behaviour using single compon...


Ecological Contexts in Adolescent Pregnancy: The Role of Individual, Sociodemog...

Araújo-Pedrosa, A; Pires, R; Carvalho, P; Canavarro, MC; Dattilio, F

Adolescent pregnancy appears today as an intricate tapestry where different dimensions interact. In our study we examined the associations between individual, sociodemographic, familial, and relational variables and their impact on the occurrence of pregnancy and adolescents’ adjustment to it. Participants were Portuguese pregnant and non-pregnant adolescents (N = 833). Ecological contexts were characterized, a...


Improvement on the mechanical properties of cork composites using suberin as co...

Fernandes, E. M.; Aroso, Ivo; Pires, R. A.; Correlo, V. M.; Pitkänen, P.; Koskimies, S.; Mano, J. F.; Reis, R. L.

New functionalized composite structures were prepared using low-density polyethylene (LDPE), cork powder and different suberins extracted from cork and birch outer bark as coupling agents to promote interfacial adhesion. The compounding was performed under reactive extrusion and samples processed by compression moulding. The morphology of the functionalized composites showed good adhesion between cork and the p...


Surface properties of extracts from cork black condensate

Pires, R. A.; Mano, J. F.; Reis, R. L.

The insulation corkboard production generates black condensate (BC), a paste-like solid waste. It is hydrophobic and has the potential to be used as protective coating. To evaluate this potential, coatings were prepared from BC extracts and their surface behavior was evaluated by contact angle (CA) measurements. The CA dynamics were recorded as a function of time; advancing CAs were also registered; the approac...


Goal Oriented C-Section in Patient with a VP Shunt

Estilita, J; Dias, S; Campos Pires, R; Marques, R; Martins, J; Quintans, A


Estudo bioquímico de possíveis portadoras de mucopolissacaridose tipo II (Síndr...

Breda, Gabriela; Schwartz, Ida Vanessa Doederlein; Matte, Ursula da Silveira; Leistner, Sandra; Lima, L.; Dieter, Tatiana; Scherer, Luciane

Data: 2007   |   Origem: OASIS br

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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia