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Optimized electro- and wet-spinning techniques for the production of polymeric ...
Puppi, D.; Piras, A. M.; Chiellini, F.; Chiellini, E.; Martins, Albino; Leonor, I. B.; Neves, N. M.; Reis, R. L.This research activity was aimed at the development of composite bioactive scaffolds made of biodegradable three-arm branched-star poly(ε-caprolactone) (∗PCL), hydroxyapatite nanoparticles (HNPs) and clodronate (CD), a bisphosphonate that has demonstrated efficacy in the treatment of various bone diseases and as an anti-inflammatory drug. During the experimental work, the processing conditions for the fabricati...
Biodegradable nanomats produced by electrospinning : expanding multifunctionali...
Ashammakhi, N.; Ndreu, A.; Piras, A. M.; Nikkola, L.; Sindelar, T.; Ylikauppila, H.; Harlin, A.; Gomes, Manuela E.; Neves, N. M.; Chiellini, E.With increasing interest in nanotechnology, development of nanofibers (n-fibers) by using the technique of electrospinning is gaining new momentum. Among important potential applications of n-fiber-based structures, scaffolds for tissue-engineering represent an advancing front. Nanoscaffolds (n-scaffolds) are closer to natural extracellular matrix (ECM) and its nanoscale fibrous structure. Although the techniqu...
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