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Insights on the safety of carotenogenic Chlorella vulgaris in rodents

Chlorella vulgaris (Cv) biomass is widely used as a traditional food in the Orient and its safety for human consumption has been proved. However, carotenogenic biomass (orange), resulting from induced stresses, needs further safety evaluation, which is the aim of this study. The preliminary toxicological characterization of Cv consisted of a single dose (mice), repeated dose studies (mice and rats) and a biodis...

Gastric cancer: an opportunity for prevention

Identification of novel nucleus pulposus markers: Interspecies variations and i...

Mesenchymal stem-cell based therapies have been proposed as novel treatments for intervertebral disc degeneration, a prevalent and disabling condition associated with back pain. The development of these treatment strategies, however, has been hindered by the incomplete understanding of the human nucleus pulposus phenotype and by an inaccurate interpretation and translation of animal to human research. This revi...

Sitagliptin delays progression of renal lesions in a rodent model of type 2 dia...

Tratamento radiocirúrgico de metástases cerebrais: a relação da histologia, loc...

Objetivo – Caracterizar clínica e estatisticamente os doentes com metástases cerebrais submetidos a radiocirurgia. Metodologia – Análise retrospetiva dos doentes com metástases cerebrais submetidos a radiocirurgia com Linac no Hospital do Meixoeiro, sendo a informação analisada no SPSS, versão 18. Resultados – Avaliaram‑se 116 doentes com metástases cerebrais. As localizações primárias de pulmão (54,30%) e mama...

A multicenter validation of an endoscopic classification with narrow band imagi...

BACKGROUND AND STUDY AIM: The reliability and external validity of narrow band imaging (NBI) in the stomach have not been described consistently. The aim of the current study was to describe and estimate the accuracy and reliability of a simplified classification system for NBI in the diagnosis of gastric lesions. METHODS: Consecutive patients undergoing NBI endoscopy at two reference centers (n=85, 33% with dy...

A multicenter validation of an endoscopic classification with narrow band imagi...

BACKGROUND AND STUDY AIM: The reliability and external validity of narrow band imaging (NBI) in the stomach have not been described consistently. The aim of the current study was to describe and estimate the accuracy and reliability of a simplified classification system for NBI in the diagnosis of gastric lesions. METHODS: Consecutive patients undergoing NBI endoscopy at two reference centers (n=85, 33% with dy...

Importance of a National arthroplasty register for Identification by medical ex...

Recurrent orthodeoxia and patent foramen ovale.

Introdução: Foramen ovale patente (FOP) ocorre em até 25% dos adultos saudáveis. Pode favorecer embolização paradoxal, enxaqueca e insuficiência respiratória (IR). Apresenta-se caso de IR e ortodeoxia por shunt direito-esquerdo via FOP sem evidência prévia de aumento da pressão intra-auricular direita. Encerramento do FOP resolveu eficazmente IR. Caso clínico: Homem, 52 anos. Mieloma múltiplo IgA/k diagnosticad...

SERVIÇOS DE SAÚDE MENTAL PARA CRIANÇAS E ADOLESCENTES: CARACTERIZAÇÃO E EXPERIÊ...

SERVIÇOS DE SAÚDE MENTAL PARA CRIANÇAS E ADOLESCENTES: CARACTERIZAÇÃO E EXPERIÊNCIA DE PERCURSO DE ACESSO Raquel Queirós Pinto1, Vânia Sousa Lima2. 1Curso de Mestrado Integrado em Psicologia , FEP/UCP. 1, 2 Faculdade de Educação e Psicologia, Universidade Católica Portuguesa (FEP/UCP), Porto. Introdução A saúde mental infanto-juvenil é uma temática cuja preocupação está cada vez mais presente na actualidade,...