Encontrados 21 documentos, a visualizar página 1 de 3
A novel method of full-thickness bladder closure with an endoscopic suturing ma...
Oliveira, Carlos; Autorino, Riccardo; Ferreira, Carlos; Cicione, Antonio; Damiano, Rocco; De Sio, Marco; Pinto, Jorge Correia"Accepted article (accepted manuscript online: 21 FEB 2014)" ; Objective To assess the feasibility of a pure endoscopic closure method for vesical perforations using fully absorbable material. Materials and methods A pilot experimental study was performed in 8 anesthetized female pigs. Four 10mm and four 20mm endoscopic full thickness cystotomies were created. An endoscopic suturing machine (RD 180®, LSI solut...
The Monocarboxylate Transporter Inhibitor α-Cyano-4-Hydroxycinnamic Acid Disrup...
Granja, Sara Costa; Santos, Filipa Morais; Gonçalves, Vera M.; Ferreira, Manuel Viana; Nogueira, Rosete; Silva, Cristina Nogueira; Pinto, Jorge CorreiaBACKGROUND/AIMS: The human embryo develops in a hypoxic environment. In this way, cells have to rely on the glycolytic pathway for energy supply, leading to an intracellular accumulation of monocarboxylates such as lactate and pyruvate. These acids have an important role in cell metabolism and their rapid transport across the plasma membrane is crucial for the maintenance of intracellular pH homeostasis. This...
Automatic pre-bended customized prosthesis for pectus excavatum minimal invasiv...
Vilaça, João L.; Rodrigues, Pedro; Pinto, Jorge CorreiaPectus excavatum is the most common deformity of the thorax. A minimally invasive surgical correction is commonly carried out to remodel the anterior chest wall, by employing an intrathoracic convex prosthesis in substernal position. The process of prosthesis modeling and bending still remains an area of improvement. The authors developed a new system, i3DExcavatum, which can automatically model and bend the ba...
The role of glycoprotein 130 family of cytokines in fetal rat lung development
Silva, Cristina Nogueira; Piairo, Paulina C.; Dias, Emanuel Carvalho; Veiga, Carla; Moura, Rute S.; Pinto, Jorge CorreiaThe glycoprotein 130 (gp130) dependent family of cytokines comprises interleukin-6 (IL-6), IL-11, leukemia inhibitory factor (LIF), cardiotrophin-like cytokine (CLC), ciliary neurotrophic factor (CNTF), cardiotrophin-1 (CT-1), and oncostatin M (OSM). These cytokines share the membrane gp130 as a common signal transducer. Recently, it was demonstrated that IL-6 promotes, whereas LIF inhibits fetal lung branching...
Variations of the soft tissue thicknesses external to the ribs in pectus excava...
Moreira, António H. J.; Pinto, Jorge Correia; Fonseca, Jaime C.; Vilaça, João L.; Rodrigues, Pedro L.; Pinho, A. C. Marques de; Rodrigues, Nuno F.BACKGROUND: Surgical repair of pectus excavatum (PE) has become more popular due to improvements in the minimally invasive Nuss procedure. The pre-surgical assessment of PE patients requires Computerized Tomography (CT), as the malformation characteristics vary from patient to patient. OBJECTIVE: This work aims to characterize soft tissue thickness (STT) external to the ribs among PE patients. It also presents ...
Local fetal lung renin-angiotensin system as a target to treat congenital diaph...
Silva, Cristina Nogueira; Dias, Emanuel Carvalho; Piairo, Paulina C.; Nunes, Susana; Baptista, Maria João Ribeiro Leite; Moura, Rute S.Antenatal stimulation of lung growth is a reasonable approach to treat congenital diaphragmatic hernia (CDH), a disease characterized by pulmonary hypoplasia and hypertension. Several evidences from the literature demonstrated a possible involvement of renin-angiotensin system (RAS) during fetal lung development. Thus, the expression pattern of renin, angiotensin-converting enzyme, angiotensinogen, type 1 (AT1)...
Leukemia inhibitory factor in rat fetal lung development : expression and funct...
Silva, Cristina Nogueira; Piairo, Paulina C.; Dias, Emanuel Carvalho; Peixoto, Francisca; Moura, Rute S.; Pinto, Jorge CorreiaConceived and designed the experiments: CN-S EC-D JC-P. Performed the experiments: CN-S PP EC-D FOP RSM. Analyzed the data: CN-S PP JC-P. Wrote the paper: CN-S PP RSM JC-P. ; Leukemia inhibitory factor (LIF) and interleukin-6 (IL-6) are members of the family of the glycoprotein 130 (gp130)-type cytokines. These cytokines share gp130 as a common signal transducer, which explains why they show some functional re...
Transthoracic single port with peroral assistance : an animal experiment to ass...
Coelho, Tiago Henriques; Soares, T. R.; Miranda, Alice; Pinto, João Moreira; Pinto, Jorge CorreiaProva tipográfica. ; Thoracoscopic repair of esophageal atresia has becoming the gold standard in many centers since it allows a better cosmetic result and avoids the musculoskeletal sequelae of a thoracotomy. Natural Orifices Transluminal Endocopic Surgery (NOTES) is a new surgical paradigm and its human application was already started in some procedures. In the present study, we explore the feasibility to pe...
Transvesical route for NOTES urological applications : advances & controversies
Lima, Estêvão Augusto Rodrigues de; Rolanda, Carla; Pinto, Jorge CorreiaNatural Orifice Transluminal Endoscopic Surgery (NOTES) has emerged recently in the experimental surgical field, innovating for the passage of luminal barrier, the absence of scars and reduction of post-operative pain. Among the various ports of access (transvaginal, transgastric, transvesical and transcolonic), this paper is an update on advances & controversies of transvesical port for NOTES Urological applic...
Transvesical natural orifice transluminal endoscopic surgery (NOTES) nephrectom...
Lima, Estêvão Augusto Rodrigues de; Branco, Frederico; Parente, Joana; Autorino, Riccardo; Pinto, Jorge CorreiaThe authorsacknowledge Karl Storz, Richard Wolf and Covidien for their support with equipment. ; What's known on the subject? and What does the study add? Until now, the transvaginal approach has been the only method of removing larger specimens from the abdominal cavity using natural orifi ce transluminal endoscopic surgery. There has been no means of extracting larger specimens in men and the means are restr...
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