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Docking studies in target proteins involved in mechanisms of antibacterial acti...

In the present work, the knowledge on target proteins of standard antibiotics was extended to antimicrobial mushroom compounds. Docking studies were performed for 34 compounds in order to evaluate their affinity to bacterial proteins that are known targets for some antibiotics with different mechanism of action: inhibitors of cell wall synthesis, inhibitors of protein synthesis, inhibitors of nucleic acids synt...

Propensity for biofilm formation by clinical isolates from urinary tract infect...

A group of biofilm-producing bacteria isolated from patients with urinary tract infections was evaluated, identifying the main factors contributing to biofilm formation. Among the 156 isolates, 58 (37.2%) were biofilm producers. The bacterial species (P<0.001), together with patient's gender (P = 0.022), were the factors with the highest influence for biofilm production. There was also a strong correlation of c...

Nanoencapsulation of bovine lactoferrin for food and biopharmaceutical applicat...

Lactoferrin has for long captured the interest of many researchers as a natural compound with a wide variety of uses. Lactoferrin is a monomeric, iron-binding 80 kDa glycoprotein, and appears to be the subfraction of whey with the best documented antiviral, antimicrobial, anticancer and immune modulating/enhancing effects. It belongs to the family of transferrin proteins, and serves to control iron levels in bo...

Effect of whey protein purity and glycerol content upon physical properties of ...

This manuscript describes the detailed characterization of edible films made from two different protein products e whey protein isolate (WPI) and whey protein concentrate (WPC), added with three levels of glycerol (Gly) e i.e. 40, 50 and 60%(w/w). The molecular structure, as well as barrier, tensile, thermal,surface and optical properties of said films were determined, in attempts to provide a better understand...

Antimicrobial activity of phenolic compounds identified in wild mushrooms, SAR ...

Aim and Methods: Although the antimicrobial activity of extracts from several mushroom species have been reported, studies with the individual compounds present in that extracts are scarce. Herein, the antimicrobial activity of different phenolic compounds identified and quantified in mushroom species from all over the world was evaluated. Furthermore, a structure activity relationship (SAR) analysis and molec...

A review on antifungal activity of mushroom (Basidiomycetes) extracts and isola...

The present review reports the antifungal activity of mushroom extracts and isolated compounds including high (e.g. peptides and proteins) and low (e.g. sesquiterpenes and other terpenes, steroids, organic acids, acylcyclopentenediones and quinolines) molecular weight compounds. Most of the studies available on literature focused on screening of antifungal activity of mushroom extracts, rather than of isolated ...

Synergistic effects between wild mushroom extracts and standard antibiotics aga...

The indiscriminate use of antibiotics and chemotherapeutic agents, among other factors, has been contributing for the development of resistant species (Andrade et al. 2006). Bacteria such as methicillin-resistant Staphylococcus aureus (MRSA) and Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli are microorganisms of concern with regard to multi-resistances. Due to this problem, there is a need to ...

Susceptibility to biofilm formation by clinical isolates from patients with uri...

Implantable medical devices help enhancing therapeutic results, saving human lives and improving life quality of patients. However, these devices can be readily colonized by bacteria and fungi, since the presence of a foreign body will reduce the number of microorganisms necessary to produce an infection (Guggenbichler et al., 2011). Accordingly, the aim of this study was to evaluate a group of biofilm producin...

Viability throughout storage of potential probiotic strains, when in contact wi...

Viability throughout storage of potential probiotic strains, when in contact wi...