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Cyclodextrins as encapsulation agents for plant bioactive compounds
Pinho, Eva; Grootveld, Martin; Soares, Graça M. B.; Henriques, MarianaAbstract Plants possess a wide range of molecules capable of improve healing: fibre, vitamins, phytosterols, and further sulphur-containing compounds, carotenoids, organic acid anions and polyphenolics. However, they require an adequate level of protection from the environmental conditions to prevent losing their structural integrity and bioactivity. Cyclodextrins are cyclic oligosaccharides arising from the de...
Antibacterial potential of Northeastern Portugal wild plant extracts and respec...
Pinho, Eva; Ferreira, Isabel C.F.R.; Barros, Lillian; Carvalho, Ana Maria; Soares, Graça; Henriques, MarianaThe present work aims to assess the antibacterial potential of phenolic extracts, recovered from plants obtained on the North East of Portugal, and of their phenolic compounds (ellagic, caffeic, and gallic acids, quercetin, kaempferol, and rutin), against bacteria commonly found on skin infections. The disk diffusion and the susceptibility assays were used to identify the most active extracts and phenolic compo...
Gallic acid and cyclodextrins : inclusion complexes and antimicrobial activity
Pinho, Eva; Soares, Graça M. B.; Henriques, MarianaGallic acid (GA), or 3,4,5-trihydroxybenzoic acid, is the commonest and simplest phenolic acid, with just one aromatic ring. This phenolic molecule has been described as antioxidant, anti-inflammatory and anti-tumour, also, antimicrobial and anti-fungal activity has been attributed to it. Besides all the GA biological activities, this compound is cheap, due to the easy plant extraction, and non-toxic. Thus, thi...
Candida albicans virulence and drug-resistance requires the O-acyltransferase G...
Ferreira, Célia; Silva, Sónia Carina; Pinho, Eva; Henriques, Mariana; Lucas, CândidaBackground GUP1 gene was primarily identified in Saccharomyces cerevisiae being connected with glycerol uptake defects in association with osmotic stress response. Soon after, Gup1p was implicated in a complex and extensive series of phenotypes involving major cellular processes. These include membrane and wall maintenance, lipid composition, bud-site selection, cytoskeleton orientation, vacuole morphology, sec...
Screening of the antibacterial activity of phenolic extracts from Portuguese no...
Pinho, Eva; Barros, Lillian; Soares, Graça M. B.; Ferreira, Isabel C. F. R.; Henriques, MarianaThermal injury, trauma, chronic ulcerations, pressure or venous stasis result in lost of skin integrity allowing the deposition and colonisation of the injury tissue by a wide range of bacteria. Skin and soft tissues infection are typically colonized by staphylococci or streptococci, but virtually any microorganism may induce tissue inflammation and immune response. The severity of the infection may range from ...
Assessment of antimicrobial activity of textiles for wound dressing: methodolog...
Pinho, Eva; Grootveld, Martin; Soares, Graça M. B.; Henriques, MarianaNormally, the skin is capable of restore the tissue integrity, after wound injury. However, the deposition of bacteria on the wound site results on infection causing pain and healing delay. To control bacteria proliferation, antimicrobial textiles have been developed, and the assessment of their activity is a required step. Although, several standard methods were published to assess textiles antimicrobial activ...
Antimicrobial activity assessment of textiles : standard methods comparison
Pinho, Eva; Magalhães, Lúcia; Henriques, Mariana; Oliveira, RosárioAntimicrobial fabrics are increasingly important in a great variety of applications and thus several standard methods to evaluate their efficiency have been developed. However, there is no consensus on the most adequate method to be used. Therefore, aim of this work was to compare the practical applicability of the best known standards: AATCC 147, ISO 20645:2004, AATCC:100 and JIS L 1902. Four samples, with dif...
Development of biofunctional textiles by the application of resveratrol to cott...
Pinho, Eva; Henriques, Mariana; Oliveira, Rosário; Dias, Alberto Carlos Pires; Soares, Graça M. B.The goal of this work was to create a new generation of greener fabrics made of natural materials. For that, resveratrol (Res), obtained from Polygonum cuspidatum extract and known to have antibacterial, antifungal, and anti-inflammatory activity, was applied by an exhaustion method to cotton, bamboo, and silk knit fabrics. The fabrics adsorption behavior was tested and the amount of Res adsorbed was determined...
Development of biofunctional textiles by the application of resveratrol to cott...
Pinho, Eva; Henriques, Mariana; Oliveira, Rosário; Dias, Alberto Carlos Pires; Soares, Graça M. B.The goal of this work was to create a new generation of greener fabrics made of natural materials. For that, resveratrol (Res), obtained from Polygonum cuspidatum extract and known to have antibacterial, antifungal, and anti-inflammatory activity, was applied by an exhaustion method to cotton, bamboo, and silk knit fabrics. The fabrics adsorption behavior was tested and the amount of Res adsorbed was determined...
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