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Human periprostatic adipose tissue promotes prostate cancer aggressiveness in v...
Ribeiro, Ricardo; Monteiro, Cátia; Cunha, Virgínia; Oliveira, Maria José; Freitas, Mariana; Fraga, Avelino; Príncipe, Paulo; Lobato, CarlosBackground - Obesity is associated with prostate cancer aggressiveness and mortality. The contribution of periprostatic adipose tissue, which is often infiltrated by malignant cells, to cancer progression is largely unknown. Thus, this study aimed to determine if periprostatic adipose tissue is linked with aggressive tumor biology in prostate cancer. Methods - Supernatants of whole adipose tissue (explants) or ...
Trends in prostate cancer mortality in Portugal (1980-2006).
Bastos, Joana; Botelho, Francisco; Pina, Francisco; Lunet, NunoIn the last decade prostate cancer mortality declined in several countries. We aimed to quantify the variation in prostate cancer mortality rates, in Portugal (1980-2006) and in different regions of the country (1992-2005).Prostate cancer mortality rates and number of deaths were obtained from the World Health Organization (1980-2003), and from the publication Risco de Morrer em Portugal (2004-2006). The latter...
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