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ERBB2 in Cat Mammary Neoplasias Disclosed a Positive Correlation between RNA an...

Santos, Sara; Batista, Claudia; Abreu, Rui M.V.; Bastos, Estela; Amorim, Irina; Gut, Ivo G.; Gartner, Fátima; Chaves, Raquel

Human ERBB2 is a proto-oncogene that codes for the erbB-2 epithelial growth factor receptor. In human breast cancer (HBC), erbB-2 protein overexpression has been repeatedly correlated with poor prognosis. In more recent works, underexpression of this gene has been described in HBC. Moreover, it is also recognised that oncogenes that are commonly amplified or deleted encompass point mutations, and some of these ...

Data: 2014   |   Origem: Biblioteca Digital do IPB

Sequence Variants and Haplotype Analysis of Cat ERBB2 Gene: A Survey on Spontan...

Santos, Sara; Bastos, Estela; Baptista, Cláudia S.; Sá, Daniela; Caloustian, Christophe; Guedes-Pinto, Henrique; Gärtner, Fátima; Gut, Ivo G.

Data: 2012   |   Origem: Repositório da UTAD

Sequence variation and mRNA expression of the TWIST1 gene in cats with mammary ...

Baptista, Cláudia S.; Santos, Sara; Laso, António; Bastos, Estela; ¿?vila, Sílvia; Guedes-Pinto, Henrique; Gärtner, Fátima; Gut, Ivo G.

Data: 2012   |   Origem: Repositório da UTAD

Feline Endometrial Adenocarcinomas

Saraiva, Ana Laura; Payan-Carreira, Rita; Gärtner, Fátima; Pires, Maria dos Anjos

Endometrial adenocarcinomas are considered to be rare in domestic animals, in particular comparing to non-epithelial tumours of the uterus such as leiomyoma, in part because they are likely underdiagnosed. In cats, though uterus was the most common site for genital tract tumours, endometrial adenocarcinomas were found to be rare in all available references. In the study presented herein, forty feline primary en...

Data: 2012   |   Origem: Repositório da UTAD

Bacterial cellulose : long-term biocompatibility studies

Pértile, Renata Aparecida Nedel; Moreira, Susana; Costa, Rui M. Gil da; Correia, Alexandra; Guardão, Luísa; Gartner, Fátima; Vilanova, Manuel

The bacterial cellulose (BC) secreted by G. xylinus is a network of pure cellulose nanofibers, which has high crystallinity, wettability and mechanical strength. These characteristics make BC an excellent material for tissue engineering constructs, noteworthy for artificial vascular grafts. In this work, the in vivo biocompatibility of BC membranes produced by two G. xylinus strains was analyzed through histolo...


TWIST1 Gene: First Insights in Felis catus

Baptista, Cláudia S.; Bastos, Estela; Santos, Sara; G. Gut, Ivo; Guedes-Pinto, Henrique; Gartner, Fatima; Chaves, Raquel

Data: 2010   |   Origem: Repositório da UTAD

TWIST1 oncogene: Comparative Studies, Sequence Variations and mRNA expression i...

Baptista, Cláudia S.; Santos, Sara; Gut, Ivo; Guedes-Pinto, Henrique; Gärtner, Fátima; Chaves, Raquel

Data: 2010   |   Origem: Repositório da UTAD

Candidate genes for cat mammary tumor: a survey from comparative genomic hybrid...

Borges, A.; Chaves, Raquel; Santos, Sara; Gärtner, Fátima; Guedes-Pinto, Henrique; Adega, Filomena

Data: 2010   |   Origem: Repositório da UTAD

In vivo biocompatibility and biodegradability of dextrin-based hydrogels

Moreira, Susana; Costa, Rui M. Gil da; Guardão, Luisa; Gartner, Fátima; Vilanova, Manuel; Gama, F. M.

The in vivo biocompatibility of dextrin hydrogels obtained by polymerization of dextrin-hydroxyethylmethacrylate (dextrin-HEMA) and dextrin-vinyl acrylate (dextrin-VA) are reported in this work. The histological analysis of subcutaneous implants of these hydrogels, featuring inflammatory and reabsorption events, were carried out over a 16-week period in mice. The dextrin-HEMA hydrogel was quickly and completely...


An efficient protocol for genomic DNA extraction from formalin-fixed paraffin-e...

Santos, Sara; Sá, Daniela; Bastos, Estela; Guedes-Pinto, Henrique; Gut, Ivo; Gärtner, Fátima; Chaves, Raquel

Data: 2009   |   Origem: Repositório da UTAD

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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia