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Non-hematopoietic cells contribute to protective tolerance to Aspergillus fumig...
Luca, Antonella De; Bozza, Silvia; Zelante, Teresa; Zagarella, Silvia; Angelo, Carmen de; Perruccio, Katia; Vacca, Carmine; Carvalho, AgostinhoInnate responses combine with adaptive immunity to generate the most effective form of anti-Aspergillus immune resistance. Whereas the pivotal role of dendritic cells in determining the balance between immunopathology and protective immunity to the fungus is well established, we determined that epithelial cells (ECs) also contributes to this balance. Mechanistically, EC-mediated protection occurred through a To...
Data: 2010
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Origem: RepositóriUM - Universidade do Minho
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